Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCNA | P12004 | 13/20 | 0.66 |
| ▸ | LIG1 | P18858 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | THRA | P10827 | 3/20 | 0.51 |
| ▸ | PPARG | P37231 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GABRP | O00591 | 1/20 | 0.51 |
| ▸ | GABRD | O14764 | 1/20 | 0.51 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.51 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.51 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.51 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.51 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10878718 | 0.88 | PCNA (0.69) | PCNALIG1THRBLMNAMEN1 | |
| SCHEMBL10878720 | 0.88 | PCNA (0.69) | PCNALIG1THRBLMNAMEN1 | |
| SCHEMBL6995423 | 0.86 | THRB (0.65) | PCNATHRBLMNAMEN1KMT2A | |
| SCHEMBL11077737 | 0.84 | PCNA (0.58) | PCNALIG1THRBLMNAMEN1 | |
| SCHEMBL11077740 | 0.84 | PCNA (0.58) | PCNALIG1THRBLMNAMEN1 | |
| SCHEMBL13670909 | 0.80 | PCNA (0.58) | PCNALIG1THRBLMNATHRA | |
| SCHEMBL5177568 | 0.80 | PCNA (0.58) | PCNALIG1THRBLMNATHRA | |
| SCHEMBL5177663 | 0.80 | PCNA (0.58) | PCNALIG1THRBLMNATHRA | |
| SCHEMBL445767 | 0.80 | PCNA (1.00) | PCNALIG1THRBLMNAMEN1 | |
| SCHEMBL1487713 | 0.80 | PCNA (1.00) | PCNALIG1THRBLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061956-B1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO SPA (IT) | 2002-12-11 | — | — | EP | claimed |
| US-6337064-B1 | USED AS CONTRAST AGENT IN MAGNETIC RESONANCE IMAGING, MEDICAL DIAGNOSIS | DIBRA S.P.A. (IT) | 2002-01-08 | — | — | US | claimed |
| EP-1061956-B1 | MANGANESE CHELATES WITH HIGH RELAXIVITY IN SERUM | BRACCO SPA (IT) | 2002-12-11 | — | — | EP | disclosed |
| US-6337064-B1 | USED AS CONTRAST AGENT IN MAGNETIC RESONANCE IMAGING, MEDICAL DIAGNOSIS | DIBRA S.P.A. (IT) | 2002-01-08 | — | — | US | disclosed |