SCHEMBL1115191

SCHEMBL1115191

O=C(O)C(Cc1cc(I)c(Oc2ccc(O)cc2)c(I)c1I)NI

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PCNA P12004 15/20 0.52
LIG1 P18858 1/20 0.43
THRB P10828 4/20 0.40
THRA P10827 3/20 0.40
LMNA P02545 2/20 0.40
CYP2D6 P10635 1/20 0.40
TSHR P16473 1/20 0.40
MEN1 O00255 1/20 0.40
GABRP O00591 1/20 0.40
GABRD O14764 1/20 0.40
ABCB11 O95342 1/20 0.40
F2 P00734 1/20 0.40
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
GABRG2 P18507 1/20 0.40
GABRB3 P28472 1/20 0.40
ADORA1 P30542 1/20 0.40
GABRA5 P31644 1/20 0.40
GABRA3 P34903 1/20 0.40
PPARG P37231 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4926016 0.91 PCNA (0.52) PCNALIG1THRBTHRALMNA
SCHEMBL8988780 0.85 PCNA (0.47) PCNALIG1THRBTHRALMNA
SCHEMBL11226810 0.85 PCNA (0.47) PCNALIG1THRBTHRALMNA
SCHEMBL10878720 0.84 PCNA (0.69) PCNALIG1THRBTHRALMNA
SCHEMBL10878718 0.84 PCNA (0.69) PCNALIG1THRBTHRALMNA
SCHEMBL31368013 0.83 PCNA (0.71) PCNALIG1THRBTHRALMNA
SCHEMBL34943 0.83 PCNA (0.71) PCNALIG1THRBTHRALMNA
SCHEMBL2679290 0.82 PCNA (0.70) PCNALIG1THRBTHRALMNA
SCHEMBL5501440 0.82 PCNA (0.70) PCNALIG1THRBTHRALMNA
SCHEMBL9222347 0.81 PCNA (0.44) PCNALMNACYP2D6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118355023-A Method for producing therapeutic immune cells with enhanced metabolic adaptation and compositions thereof 得克萨斯大学体系董事会 2024-07-16 CN disclosed
CN-118302176-A Peptides targeting MAGE-A4 antigen and engineered T cell receptors and methods of use 得克萨斯州大学系统董事会 2024-07-05 CN disclosed
CN-118265721-A Peptides targeting NDC80 antigen and engineered T cell receptors and methods of use 得克萨斯州大学系统董事会 2024-06-28 CN disclosed
CN-118234847-A Thymocyte and preparation method thereof 胸腺疗法公司 2024-06-21 CN disclosed
CN-118103062-A Peptides targeting SARS-COV-2 antigen and engineered T cell receptors and methods of use thereof 德克萨斯大学体系董事会 2024-05-28 CN disclosed
CN-117957012-A Peptides targeting FANCI, RAD51 and PBK antigens and engineered T cell receptors and methods of use 得克萨斯州大学系统董事会 2024-04-30 CN disclosed
CN-117897405-A Polypeptide targeting CD 70-positive cancer 得克萨斯大学体系董事会 2024-04-16 CN disclosed
CN-117545492-A Methods of engineering immune cells with reduced autophagy 贝勒医学院 2024-02-09 CN disclosed
CN-117425482-A Engineered T cell receptors targeting EGFR antigens and methods of use 得克萨斯州大学系统董事会 2024-01-19 CN disclosed
CN-117425665-A Methods and compositions comprising MHC class I peptides 得克萨斯州大学系统董事会 2024-01-19 CN disclosed
EP-1635651-A1 METHODS FOR HYPERTHYROIDISM IN A CAT AND COMPOSITION COMPRISING LIMITED IODINE Hill's Pet Nutrition Inc. (US) 2006-03-22 EP disclosed
EP-1635652-A1 METHODS FOR PREVENTING HYPERTHYROIDISM IN A CAT AND COMPOSITION COMPRISING LIMITED SELENIUM AN IODINE Hill's Pet Nutrition Inc. (US) 2006-03-22 EP disclosed
US-20050064016-A1 Methods for dietary management of cats to avoid hyperthyroidism HILL'S PET NUTRITION, INC. 2005-03-24 US disclosed
WO-2004112498-A1 METHODS FOR HYPERTHYROIDISM IN A CAT AND COMPOSITION COMPRISING LIMITED IODINE HILL'S PET NUTRITION, INC. (US) 2004-12-29 WO disclosed
WO-2004112499-A1 METHODS FOR PREVENTING HYPERTHYROIDISM IN A CAT AND COMPOSITION COMPRISING LIMITED SELENIUM AN IODINE HILL'S PET NUTRITION, INC. (US) 2004-12-29 WO disclosed
US-4431741-A Hypothyroid control serum BAXTER TRAVENOL LABORATORIES, INC. (US) 1984-02-14 US disclosed
US-4273865-A Insolubilized biochemical materials BYK-MALLINCKRODT CHEMISCHE PRODUKTE GMBH (DE) 1981-06-16 US disclosed
US-4225576-A Combined radioimmunoassay for triiodothyronine and thyroxine MILES LABORATORIES, INC. (US) 1980-09-30 US disclosed
US-3995019-A FOR RADIOIMMUNOASSAY CONSISTING OF A SPECIFIC ANTIBODY RADIOLABELED, ANTIGEN, POLYETHYLENE GLYCOL, AND GAMMA GLOBULIN BAXTER TRAVENOL LABORATORIES, INC. (US) 1976-11-30 US disclosed
US-3962039-A PEPSIN CENTER FOR LABORATORY MEDICINE (US) 1976-06-08 US disclosed