SCHEMBL10879003

SCHEMBL10879003

C[SiH](N(c1ccccc1)c1ccccc1)N(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.42
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
HTT P42858 1/20 0.40
ALDH1A1 P00352 5/20 0.36
ALOX15 P16050 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
TSHR P16473 3/20 0.34
FAAH O00519 1/20 0.34
PHGDH O43175 1/20 0.34
MGLL Q99685 1/20 0.34
GLA P06280 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1276853 0.82 KMT2A (0.40) NPSR1MEN1KMT2AHTTALDH1A1
SCHEMBL9621566 0.76 MEN1 (0.36) NPSR1MEN1KMT2AHTTALDH1A1
SCHEMBL10652728 0.75 ALDH1A1 (0.39) NPSR1MEN1KMT2AHTTALDH1A1
SCHEMBL9621445 0.74 ALDH1A1 (0.39) MEN1KMT2AHTTALDH1A1L3MBTL1
SCHEMBL12506407 0.72 ALDH1A1 (0.33) NPSR1MEN1KMT2AHTTALDH1A1
SCHEMBL10393863 0.71 ALDH1A1 (0.56) NPSR1MEN1KMT2AHTTALDH1A1
SCHEMBL1276854 0.71 KMT2A (0.40) NPSR1MEN1KMT2AHTTALDH1A1
SCHEMBL10654718 0.70 TSHR (0.40) MEN1KMT2AHTTALDH1A1L3MBTL1
SCHEMBL6865133 0.65 MEN1 (0.52) NPSR1MEN1KMT2AHTTALDH1A1
SCHEMBL20385081 0.65 MEN1 (0.52) NPSR1MEN1KMT2AHTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0098911-B1 IMPROVED PROCESS FOR THE PREPARATION OF OXIMATOHYDRIDOSILANES AND AMINOXYHYDRIDOSILANES UNION CARBIDE CORPORATION (US) 1986-04-16 EP disclosed
EP-0112434-A2 Hydrogen bearing silyl carbamates UNION CARBIDE CORPORATION (US) 1984-07-04 EP disclosed
EP-0098911-A1 Improved process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
EP-0098912-A1 Process for the preparation of alkoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1984-01-25 EP disclosed
US-4400526-A Hydrogen bearing silyl carbamates UNION CARBIDE CORPORATION (US) 1983-08-23 US disclosed
US-4395564-A REACTING AN ALCOHOL WITH SILYL-AMINE UNION CARBIDE CORPORATION (US) 1983-07-26 US disclosed
US-4384131-A Process for the preparation of oximatohydridosilanes and aminoxyhydridosilanes UNION CARBIDE CORPORATION (US) 1983-05-17 US disclosed