Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10654718 | 0.78 | TSHR (0.40) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL10879003 | 0.74 | NPSR1 (0.42) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL1276853 | 0.74 | KMT2A (0.40) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL10652764 | 0.70 | TSHR (0.38) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL9621566 | 0.68 | MEN1 (0.36) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL10652728 | 0.68 | ALDH1A1 (0.39) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL11704619 | 0.67 | TSHR (0.48) | ALDH1A1TSHRGLATP53MEN1 | |
| SCHEMBL11097679 | 0.67 | GAA (0.41) | ALDH1A1TSHRGLATP53MAPT | |
| SCHEMBL11097240 | 0.67 | TSHR (0.43) | ALDH1A1TSHRGLATP53MEN1 | |
| Butane SCHEMBL28208271 | 0.66 | ALDH1A1 (0.55) | ALDH1A1TSHRGLATP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0228095-B1 | PROCESS FOR THE PREPARATION OF OLEFINIC SILANES AND SILOXANES | UNION CARBIDE CORPORATION (US) | 1992-01-22 | — | — | EP | disclosed |
| EP-0228095-A2 | Process for the preparation of olefinic silanes and siloxanes | UNION CARBIDE CORPORATION (US) | 1987-07-08 | — | — | EP | disclosed |
| US-4668812-A | Process for the preparation of olefinic silanes and siloxanes | UNION CARBIDE CORPORATION (US) | 1987-05-26 | — | — | US | disclosed |