SCHEMBL1087909

SCHEMBL1087909

O=C(Cl)C1CCC(Cl)CC1

nearest known ligand 0.33

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 3/20 0.33
CHRNA3 P32297 3/20 0.33
CHRNA4 P43681 3/20 0.33
CHRNB4 P30926 2/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNB3 Q05901 1/20 0.32
CHRNA6 Q15825 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
HSD17B10 Q99714 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
HPGD P15428 1/20 0.31
ACE P12821 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL890380 0.93 CHRNB2 (0.36) CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7
SCHEMBL4279 0.93
SCHEMBL1506461 0.93 CHRNB2 (0.36) CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7
SCHEMBL1060400 0.93 CHRNB2 (0.36) CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7
Hydrochloric Acid SCHEMBL1880027 0.90
SCHEMBL11819878 0.88
Bicarbonate SCHEMBL27911841 0.87 LMNA (0.35) CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7
SCHEMBL13044828 0.84 CHRNB2 (0.37) CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7
SCHEMBL21391917 0.84 CES2 (0.43) CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7
SCHEMBL2153805 0.84 CHRNB2 (0.37) CHRNB2CHRNA3CHRNA4CHRNB4CHRNA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3279181-B1 METHOD FOR PRODUCING A MIXTURE OF A POLYMERIZABLE COMPOUND ZEON CORP (JP) 2021-08-04 EP disclosed
US-10934246-B2 Mixture of polymerizable compound and method of producing the same ZEON CORPORATION (JP) 2021-03-02 US disclosed
US-20200148622-A1 MIXTURE OF POLYMERIZABLE COMPOUND AND METHOD OF PRODUCING THE SAME ZEON CORPORATION (JP) 2020-05-14 US disclosed
US-10577306-B2 Mixture of polymerizable compound and method of producing the same ZEON CORPORATION (JP) 2020-03-03 US disclosed
US-20180099921-A1 MIXTURE OF POLYMERIZABLE COMPOUND AND METHOD OF PRODUCING THE SAME ZEON CORPORATION (JP) 2018-04-12 US disclosed
EP-3279181-A1 MIXTURE OF POLYMERIZABLE COMPOUND AND METHOD FOR PRODUCING SAME Zeon Corporation (JP) 2018-02-07 EP disclosed
US-20160053116-A1 POLYMER SOLUTION, POLYMER FILM, STACKED COMPOSITE, DISPLAY ELEMENT, OPTICAL ELEMENT, ILLUMINATION ELEMENT, AND PRODUCTION METHOD THEREFOR SUMITOMO BAKELITE CO., LTD. (JP) 2016-02-25 US disclosed
EP-1564237-B1 ALICYCLIC OR AROMATIC POLYAMIDES, POLYAMIDE FILMS, OPTICAL MEMBERS MADE BY USING THE SAME, AND POLYAMIDE COPOLYMERS TORAY INDUSTRIES (JP) 2013-12-25 EP disclosed
US-8153753-B2 Alicyclic or aromatic polyamides, polyamide films, optical members made by using the same, and polyamide copolymers TORAY INDUSTRIES, INC. (JP) 2012-04-10 US disclosed
US-20060106193-A1 Alicyclic or aromatic polyamides, polyamide films, optical members made by using the same, and polyamide copolymers TORAY INDUSTRIES,. (JP) 2006-05-18 US disclosed
WO-1992020227-A1 SUBSTITUTED ORALLY EFFECTIVE ION CHELATORS RELATED TO DEFEROXAMINE ORAL-D (US) 1992-11-26 WO disclosed
US-5047421-A Treating trivalent metal overload conditions in humans ORAL-D (US) 1991-09-10 US disclosed
US-5015664-A Orally effective ion chelators related to deferoxamine ORAL D (US) 1991-05-14 US disclosed
US-4684482-A DEFEROXAMINE DERIVATIVES ORAL-D (L.P.) (US) 1987-08-04 US disclosed
US-4671901-A DIFEROXAMINE DERIVATIVES FOR REDUCTION OF METAL ION TUSSUE OV ERLOAD ORAL-D (US) 1987-06-09 US disclosed
EP-0171414-A1 ORALLY EFFECTIVE ION CHELATORS RELATED TO DEFEROXAMINE. ORAL D (US) 1986-02-19 EP disclosed
WO-1985003290-A1 ORALLY EFFECTIVE ION CHELATORS RELATED TO DEFEROXAMINE ORAL-D (US) 1985-08-01 WO disclosed
US-4014922-A CYCLOPROPYL SUBSTITUTED ESTERS; MITICIDES ZOECON CORPORATION (US) 1977-03-29 US disclosed
US-3954730-A ANTIBIOTICS BAYER AKTIENGESELLSCHAFT (DT) 1976-05-04 US disclosed
US-3948961-A CYCLOPROPYL ALKYL CARBOXYLATES, MITICIDE, INSECTICIDE ZOECON CORPORATION (US) 1976-04-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10934246-B2 Mixture of polymerizable compound and method of producing the same DDT, CA4, DNMT3B CHRNB2 2215/4885CHRNA3 2456/4885CHRNA4 1372/4885
US-20180099921-A1 MIXTURE OF POLYMERIZABLE COMPOUND AND METHOD OF PRODUCING THE SAME DDT, CA4, DNMT3B CHRNB2 2215/4885CHRNA3 2456/4885CHRNA4 1372/4885
US-20200148622-A1 MIXTURE OF POLYMERIZABLE COMPOUND AND METHOD OF PRODUCING THE SAME DDT, CA4, DNMT3B CHRNB2 2215/4885CHRNA3 2456/4885CHRNA4 1372/4885
US-10577306-B2 Mixture of polymerizable compound and method of producing the same DDT, CA4, DNMT3B CHRNB2 2215/4885CHRNA3 2456/4885CHRNA4 1372/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.