SCHEMBL4279

SCHEMBL4279

O=C(Cl)C1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1060400 1.00 CHRNB2 (0.36)
SCHEMBL890380 1.00 CHRNB2 (0.36)
SCHEMBL1506461 1.00 CHRNB2 (0.36)
Hydrochloric Acid SCHEMBL1880027 0.96
Bicarbonate SCHEMBL27911841 0.93 LMNA (0.35)
SCHEMBL1087909 0.93 CHRNB2 (0.33)
SCHEMBL21391917 0.90 CES2 (0.43)
SCHEMBL2153805 0.90 CHRNB2 (0.37)
SCHEMBL13044828 0.90 CHRNB2 (0.37)
Methylene Chloride SCHEMBL28166563 0.90

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 14464 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3504196-B1 PROCESSES FOR PREPARING OLAPARIB SCINOPHARM TAIWAN LTD (TW) 2026-04-08 EP claimed
US-12552931-B2 Dihydroxy lactam based polymers, compositions and applications thereof ISP INVESTMENTS LLC (US) 2026-02-17 US claimed
CN-120142484-A Method for detecting relevant impurities of acyl chloride compounds 四川科伦药物研究院有限公司 2025-06-13 CN claimed
CN-120081836-A Response near infrared fluorescent probe targeting butyrylcholinesterase and beta amyloid, and preparation method and application thereof 湖北大学 2025-06-03 CN claimed
CN-119899184-A Beta-carboline compound, preparation method thereof and application thereof in resisting Alzheimer disease 中国人民解放军北部战区总医院 2025-04-29 CN claimed
CN-119775112-A Compound containing polybrominated diphenyl ether structure, and preparation method and application thereof 烟台新药创制山东省实验室 2025-04-08 CN claimed
CN-119591494-A Synthesis process of cyclopropanecarbonyl chloride 安道麦安邦(江苏)有限公司 2025-03-11 CN claimed
CN-119504420-A Preparation method of cyclopropanecarbonyl chloride by using phosphorus trichloride as chlorinating agent 浙江万盛股份有限公司 2025-02-25 CN claimed
CN-119431312-A Enzymatic serum albumin fluorescent probe and synthesis and application thereof 河北大学 2025-02-14 CN claimed
CN-118812351-B Preparation method of cyclopropanecarbonyl chloride 山东国邦药业有限公司 2025-01-28 CN claimed
EP-0312124-A2 Process for the preparation of optically-active cyanomethyl esters E.I. DU PONT DE NEMOURS AND COMPANY (US) 1989-04-19 EP claimed
US-4723027-A TREATING AN ALDEHYDE WITH HYDROGEN CYANIDE IN THE PRESENCE OF CYCLO(D-PHENYLALANYL-D-HISTIDINE)CATALYST E. I. DU PONT DE NEMOURS AND COMPANY (US) 1988-02-02 US claimed
EP-0112133-B1 5-PHENYLETHENYLBENZIMIDAZOLES SMITHKLINE BECKMAN CORPORATION (US) 1987-10-21 EP claimed
US-4613668-A Short total synthesis or morphinan compounds which uses cyclization of a cycloalkylcarbonyl compound selected from cyclopropylcarbonyl and cyclobutylcarbonyl THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1986-09-23 US claimed
EP-0155424-A1 A total synthesis of morphinan compounds by cyclization of cycloalkylcarbonyl compounds THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce (US) 1985-09-25 EP claimed
EP-0112133-A1 5-Phenylethenylbenzimidazoles SMITHKLINE BECKMAN CORPORATION (US) 1984-06-27 EP claimed
EP-0109681-A2 process for the preparation of optically-active cyanomethyl esters E.I. DU PONT DE NEMOURS AND COMPANY (US) 1984-05-30 EP claimed
EP-0007070-B1 2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS HAVING DOPAMINE RECEPTOR BLOCKING ACTIVITY SMITHKLINE BECKMAN CORPORATION (US) 1983-01-19 EP claimed
US-4211727-A CADMIUM BOROHYDRIDE COMPLEX AS REDUCING AGENT SHELL OIL COMPANY (US) 1980-07-08 US claimed
EP-0007070-A1 2,3,4,5-Tetrahydro-1H-3-Benzazepines, process for their production and pharmaceutical compositions having dopamine receptor blocking activity SMITHKLINE BECKMAN CORPORATION (US) 1980-01-23 EP claimed