SCHEMBL10879274

SCHEMBL10879274

Cc1ccc(S(=O)(=O)C2CCCCNC2=O)cc1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.47
ALDH1A1 P00352 2/20 0.42
MAPT P10636 2/20 0.42
CYP3A4 P08684 1/20 0.42
TSHR P16473 1/20 0.42
CRBN Q96SW2 2/20 0.42
DDB1 Q16531 1/20 0.42
PSEN1 P49768 8/20 0.41
PSEN2 P49810 8/20 0.41
APH1B Q8WW43 8/20 0.41
NCSTN Q92542 8/20 0.41
APH1A Q96BI3 8/20 0.41
PSENEN Q9NZ42 8/20 0.41
ACHE P22303 1/20 0.39
MMP2 P08253 1/20 0.37
MMP9 P14780 1/20 0.37
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10884103 0.85 PSEN1 (0.48) ALDH1A1MAPTCRBNDDB1PSEN1
SCHEMBL10878205 0.85 PSEN1 (0.53) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL10876701 0.85 HTR6 (0.44) ALDH1A1MAPTCYP3A4TSHRCRBN
SCHEMBL10879160 0.84 MAPT (0.59) ALDH1A1MAPTPSEN1PSEN2APH1B
SCHEMBL10878290 0.82 PSEN1 (0.50) MAPTCRBNDDB1PSEN1PSEN2
SCHEMBL10879278 0.81 ACHE (0.42) MAPTCRBNDDB1PSEN1PSEN2
SCHEMBL10876689 0.78 PSEN1 (0.50) CYP3A4PSEN1PSEN2APH1BNCSTN
SCHEMBL4668674 0.75 RAB9A (0.56) RAB9AALDH1A1MAPTCYP3A4TSHR
SCHEMBL15172491 0.75 RAB9A (0.56) RAB9AALDH1A1MAPTCYP3A4TSHR
SCHEMBL7420435 0.75 RAB9A (0.39) RAB9AALDH1A1MAPTCYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0093949-B1 SULFINYL AND SULFONYLAZACYCLOHEPTAN-2-ONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS FEED ADDITIVES BAYER AG (DE) 1986-03-12 EP disclosed