Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10879274 | 0.75 | RAB9A (0.47) | RAB9ACRBNALDH1A1TSHRACHE | |
| SCHEMBL22142711 | 0.74 | ACHE (0.43) | ALDH1A1TSHRACHECYP3A4POLB | |
| SCHEMBL10878314 | 0.71 | CRBN (0.38) | RAB9ACRBNALDH1A1TSHRACHE | |
| SCHEMBL19318746 | 0.71 | ACHE (0.46) | ALDH1A1TSHRACHECYP3A4POLB | |
| SCHEMBL19318741 | 0.71 | ALDH1A1 (0.46) | ALDH1A1TSHRACHECYP3A4POLB | |
| SCHEMBL14855597 | 0.70 | ALDH1A1 (0.54) | RAB9AALDH1A1TSHRCYP3A4POLB | |
| SCHEMBL14856021 | 0.70 | ALDH1A1 (0.54) | RAB9AALDH1A1TSHRCYP3A4POLB | |
| SCHEMBL22548444 | 0.70 | ALDH1A1 (0.49) | ALDH1A1TSHRACHECYP3A4POLB | |
| SCHEMBL15373619 | 0.69 | ALDH1A1 (0.47) | ALDH1A1TSHRACHECYP3A4POLB | |
| SCHEMBL10654240 | 0.68 | ALDH1A1 (0.50) | ALDH1A1TSHRACHECYP3A4POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0815084-A1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1998-01-07 | — | — | EP | claimed |
| WO-1996029313-A1 | LACTAM-CONTAINING HYDROXAMIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE AS INHIBITORS OF MATRIX METALLOPROTEASE | THE PROCTER & GAMBLE COMPANY (US) | 1996-09-26 | — | — | WO | claimed |