Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10876477 | 0.81 | FSCN1 (0.36) | SMN1; SMN2 | |
| SCHEMBL10879477 | 0.81 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL10883141 | 0.77 | PTPN1 (0.31) | — | |
| SCHEMBL10878458 | 0.76 | FSCN1 (0.33) | — | |
| SCHEMBL10876630 | 0.75 | LMNA (0.39) | POLB | |
| Hydrochloric Acid SCHEMBL10816153 | 0.74 | LMNA (0.38) | SMN1; SMN2POLB | |
| SCHEMBL9616491 | 0.73 | NOS3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL10879822 | 0.72 | NOS3 (0.30) | — | |
| SCHEMBL11033315 | 0.71 | POLB (0.42) | SMN1; SMN2POLB | |
| SCHEMBL5154555 | 0.70 | GABRA1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081924-B1 | TOPICAL COMPOSTIONS FOR LOWERING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1986-02-19 | — | — | EP | disclosed |
| US-4517199-A | TREATMENT OF GLAUCOMA | ALCON LABORATORIES, INC. (US) | 1985-05-14 | — | — | US | disclosed |
| US-4515800-A | GLAUCOMA | ALCON MANUFACTURING, LTD. | 1985-05-07 | — | — | US | disclosed |
| EP-0081924-A1 | Topical compostions for lowering intraocular pressure | ALCON LABORATORIES, INC. (US) | 1983-06-22 | — | — | EP | disclosed |