Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10879822 | 0.98 | NOS3 (0.30) | NOS3NOS1NOS2 | |
| SCHEMBL10883141 | 0.82 | PTPN1 (0.31) | — | |
| SCHEMBL5154555 | 0.78 | GABRA1 (0.46) | — | |
| SCHEMBL9616494 | 0.77 | HTT (0.49) | — | |
| SCHEMBL10856764 | 0.76 | ALDH1A1 (0.32) | — | |
| SCHEMBL10879292 | 0.75 | POLB (0.38) | NOS3NOS1NOS2 | |
| SCHEMBL10876630 | 0.74 | LMNA (0.39) | — | |
| Hydrochloric Acid SCHEMBL10978799 | 0.74 | ALDH1A1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL10817570 | 0.74 | POLB (0.37) | NOS3NOS1NOS2 | |
| Hydrochloric Acid SCHEMBL10817770 | 0.74 | POLB (0.37) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0081924-B1 | TOPICAL COMPOSTIONS FOR LOWERING INTRAOCULAR PRESSURE | ALCON LABORATORIES, INC. (US) | 1986-02-19 | — | — | EP | claimed |
| EP-0081924-A1 | Topical compostions for lowering intraocular pressure | ALCON LABORATORIES, INC. (US) | 1983-06-22 | — | — | EP | claimed |
| EP-0484325-A4 | AZIDO-SUBSTITUTED OCTOPAMINE AGONISTS AND THE USE THEREOF TO CONTROL INVERTEBRATE PESTS | — | 1992-06-24 | — | — | EP | disclosed |
| EP-0484325-A1 | AZIDO-SUBSTITUTED OCTOPAMINE AGONISTS AND THE USE THEREOF TO CONTROL INVERTEBRATE PESTS | THE GENERAL HOSPITAL CORPORATION (US) | 1992-05-13 | — | — | EP | disclosed |
| US-4892871-A | INSECTICIDE | THE GENERAL HOSPITAL CORPORATION (US) | 1990-01-09 | — | — | US | disclosed |
| WO-1989009542-A1 | AZIDO-SUBSTITUTED OCTOPAMINE AGONISTS AND THE USE THEREOF TO CONTROL INVERTEBRATE PESTS | THE GENERAL HOSPITAL CORPORATION (US) | 1989-10-19 | — | — | WO | disclosed |