Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.39 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10881926 | 0.99 | FAAH (0.41) | FAAHLMNAHPGDACHENPC1 | |
| SCHEMBL10881168 | 0.88 | ACHE (0.42) | FAAHLMNAHPGDACHENPC1 | |
| SCHEMBL21092400 | 0.84 | MAOB (0.43) | HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL10879509 | 0.81 | FAAH (0.46) | FAAHLMNAHPGDACHENPC1 | |
| SCHEMBL10880568 | 0.81 | MAOA (0.58) | LMNAHPGDALDH1A1 | |
| SCHEMBL10882709 | 0.79 | NPC1 (0.42) | FAAHLMNAHPGDNPC1PKM | |
| Hydrochloric Acid SCHEMBL10878890 | 0.78 | NPC1 (0.41) | FAAHLMNAHPGDNPC1PKM | |
| SCHEMBL10879784 | 0.77 | MAPT (0.55) | LMNAHPGDNPC1RAB9AMEN1 | |
| Hydrochloric Acid SCHEMBL10881949 | 0.77 | NPC1 (0.40) | LMNAHPGDNPC1PKMRAB9A | |
| SCHEMBL9621088 | 0.76 | NPC1 (0.43) | ACHENPC1PKMRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109815-B1 | IMPROVEMENTS IN AND RELATING TO SUBSTITUTED TETRAHYDRONA PHTHALENES | ELI LILLY AND COMPANY (US) | 1986-05-28 | — | — | EP | disclosed |
| EP-0109815-A1 | Improvements in and relating to substituted tetrahydrona phthalenes | ELI LILLY AND COMPANY (US) | 1984-05-30 | — | — | EP | disclosed |