SCHEMBL10883273

SCHEMBL10883273

CCCCC(CC)C[P+](c1ccccc1)(c1ccccc1)c1ccccc1.c1ccc(O[Al-](Oc2ccccc2)(Oc2ccccc2)Oc2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
CA2 P00918 1/20 0.39
CYP3A4 P08684 1/20 0.39
KDM4E B2RXH2 1/20 0.38
PRSS1 P07477 1/20 0.37
PRSS2 P07478 1/20 0.37
PRSS3 P35030 1/20 0.37
LMNA P02545 2/20 0.36
ALOX5 P09917 1/20 0.34
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
MAPK1 P28482 1/20 0.34
MAPT P10636 2/20 0.34
TP53 P04637 1/20 0.34
HIF1A Q16665 1/20 0.34
LTA4H P09960 2/20 0.34
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HDAC3 O15379 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL8095563 0.85 ALDH1A1 (0.45) ALDH1A1CA2CYP3A4KDM4EPRSS1
Hydrochloric Acid SCHEMBL8095273 0.85 ALDH1A1 (0.45) ALDH1A1CA2CYP3A4KDM4EPRSS1
Iodide SCHEMBL8529110 0.70 ALDH1A1 (0.37) ALDH1A1CA2CYP3A4KDM4EPRSS1
SCHEMBL4913490 0.69 ALDH1A1 (0.54) ALDH1A1CA2CYP3A4KDM4EPRSS1
Butyltriphenylphosphonium SCHEMBL30358591 0.69 HIF1A (0.64) ALDH1A1MAPK1MAPTHIF1AMEN1
Butyltriphenylphosphonium SCHEMBL3418099 0.68 HIF1A (0.61) ALDH1A1MAPK1MAPTHIF1AMEN1
Butyltriphenylphosphonium SCHEMBL584160 0.68 HIF1A (0.61) ALDH1A1MAPK1MAPTHIF1AMEN1
Butyltriphenylphosphonium SCHEMBL584744 0.68 HIF1A (0.61) ALDH1A1MAPK1MAPTHIF1AMEN1
Butyltriphenylphosphonium SCHEMBL8535782 0.68 HIF1A (0.61) ALDH1A1MAPK1MAPTHIF1AMEN1
Butyltriphenylphosphonium SCHEMBL1063 0.68 HIF1A (0.61) ALDH1A1MAPK1MAPTHIF1AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0072157-B1 NOVEL ORGANIC SALT COMPOSITIONS IN EXTRACTION PROCESSES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1986-10-01 EP disclosed
US-4440634-A Organic salt compositions in extraction processes EXXON RESEARCH AND ENGINEERING CO. (US) 1984-04-03 US disclosed
US-4422975-A Organic salt compositions in extraction processes EXXON RESEARCH AND ENGINEERING CO. (US) 1983-12-27 US disclosed
EP-0072157-A2 Novel organic salt compositions in extraction processes EXXON RESEARCH AND ENGINEERING COMPANY (US) 1983-02-16 EP disclosed