Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | COMT | P21964 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | METAP1 | P53582 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30818296 | 0.83 | KCNMA1 (0.41) | KDM4EHSP90AA1ALDH1A1MEN1KMT2A | |
| SCHEMBL6643350 | 0.83 | KCNMA1 (0.41) | KDM4EHSP90AA1ALDH1A1MEN1KMT2A | |
| SCHEMBL12663631 | 0.76 | KDM4E (0.50) | KDM4EHSP90AA1ALDH1A1MEN1KMT2A | |
| SCHEMBL2010937 | 0.74 | ALDH1A1 (0.40) | KDM4EHSP90AA1ALDH1A1MEN1KMT2A | |
| SCHEMBL11926273 | 0.73 | HTT (0.46) | KDM4EHSP90AA1ALDH1A1MEN1KMT2A | |
| SCHEMBL3344781 | 0.73 | KDM4E (0.46) | KDM4EHSP90AA1ALDH1A1MEN1KMT2A | |
| SCHEMBL2706312 | 0.73 | HSP90AA1 (0.58) | KDM4EHSP90AA1ALDH1A1MEN1KMT2A | |
| SCHEMBL11170566 | 0.72 | KDM4E (0.54) | KDM4EHSP90AA1ALDH1A1MEN1KMT2A | |
| SCHEMBL3249138 | 0.72 | ALDH1A1 (0.58) | KDM4EALDH1A1TDP1MAPTL3MBTL1 | |
| SCHEMBL11926120 | 0.72 | COMT (0.40) | KDM4EHSP90AA1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0034759-B1 | CHROMOGEN CEPHALOSPORINS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-01-02 | — | — | EP | claimed |
| US-4416884-A | ANTIBIOTIC, BACTERICIDE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-22 | — | — | US | disclosed |