Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 19/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29908105 | 1.00 | CASP1 (0.46) | CASP1ALDH1A1 | |
| SCHEMBL3862102 | 0.84 | ITGB3 (0.40) | — | |
| SCHEMBL3862108 | 0.84 | ITGB3 (0.40) | — | |
| SCHEMBL6564177 | 0.83 | TGM2 (0.34) | — | |
| SCHEMBL6564191 | 0.83 | TGM2 (0.34) | — | |
| SCHEMBL753950 | 0.82 | ITGA4 (0.41) | — | |
| Hydrochloric Acid SCHEMBL28591530 | 0.82 | TGM2 (0.33) | — | |
| SCHEMBL29908060 | 0.81 | ITGB3 (0.33) | ALDH1A1 | |
| SCHEMBL28836215 | 0.81 | ITGB3 (0.33) | ALDH1A1 | |
| SCHEMBL1073717 | 0.81 | ITGB2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0109044-B1 | PENEMS, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, PROCESS FOR PREPARING THEM | SCHERING CORPORATION (US) | 1986-10-15 | — | — | EP | disclosed |
| US-4540580-A | 2-[(1'R)-1'-Aminoalkyl]penems | SCHERING CORPORATION (US) | 1985-09-10 | — | — | US | disclosed |
| EP-0109044-A1 | Penems, pharmaceutical compositions containing them, process for preparing them | SCHERING CORPORATION (US) | 1984-05-23 | — | — | EP | disclosed |