SCHEMBL10884670

SCHEMBL10884670

c1ccc(-c2c[nH]nc2N=Nc2cc[nH]n2)nc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PRKCI P41743 1/20 0.35
▸ KDM4E B2RXH2 6/20 0.35
▸ LMNA P02545 3/20 0.35
▸ CCR1 P32246 2/20 0.35
▸ CCR5 P51681 2/20 0.35
▸ CCR8 P51685 2/20 0.35
▸ CYP1A2 P05177 1/20 0.35
▸ POLB P06746 1/20 0.35
▸ METAP1 P53582 1/20 0.35
▸ BLM P54132 1/20 0.35
▸ HIF1A Q16665 1/20 0.35
▸ DOHH Q9BU89 1/20 0.35
▸ P4HTM Q9NXG6 1/20 0.35
▸ METAP2 P50579 1/20 0.33
▸ NPC1 O15118 4/20 0.33
▸ RAB9A P51151 4/20 0.33
▸ ALOX15 P16050 3/20 0.32
▸ SMN1; SMN2 Q16637 3/20 0.32
▸ TDP1 Q9NUW8 3/20 0.32
▸ L3MBTL1 Q9Y468 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10803025 0.84 — —
SCHEMBL2554756 0.80 ALDH1A1 (0.30) ALDH1A1
SCHEMBL10884665 0.75 MAOA (0.55) KDM4ELMNAPOLBNPC1SMN1; SMN2
SCHEMBL5152077 0.75 LMNA (0.36) LMNAPOLBNPC1RAB9ASMN1; SMN2
SCHEMBL1876908 0.74 — —
SCHEMBL28257868 0.73 KDM4E (0.43) KDM4EPOLBNPC1RAB9AALOX15
SCHEMBL10891792 0.72 MEN1 (0.33) KDM4EPOLBRAB9AALOX15SMN1; SMN2
SCHEMBL29360772 0.71 KDM4E (0.38) PRKCIKDM4ELMNACCR1CCR5
SCHEMBL10921322 0.71 KDM4E (0.46) PRKCIKDM4ELMNACCR1CCR5
SCHEMBL10802992 0.70 MAOA (0.34) MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4619884-A Photographic products employing nondiffusible N',N'-diaromatic carbocyclic--or diaromatic heterocyclic--sulfonohydrazide compounds capable of releasing photographically useful groups EASTMAN KODAK COMPANY (US) 1986-10-28 — — US disclosed
EP-0095410-B1 PHOTOGRAPHIC ELEMENT EMPLOYING A SUBSTITUTED SULFONAMIDOPHENOL OR SULFONAMIDONAPHTHOL DYE-RELEASING COMPOUND EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-08-27 — — EP disclosed
EP-0059269-B1 PHOTOGRAPHIC ELEMENTS CONTAINING BLOCKED DYES OR BLOCKED DYE RELEASING COMPOUNDS AND PROCESSES FOR USING THEM EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-05-22 — — EP disclosed
EP-0095410-A2 Photographic element employing a substituted sulfonamidophenol or sulfonamidonaphthol dye-releasing compound EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1983-11-30 — — EP disclosed
US-4407930-A DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1983-10-04 — — US disclosed
US-4363865-A COLOR FILMS; LIGHT SENSITIVE ELEMENTS; PROCESS CONTROL EASTMAN KODAK COMPANY (US) 1982-12-14 — — US disclosed
EP-0059269-A2 Photographic elements containing blocked dyes or blocked dye releasing compounds and processes for using them EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1982-09-08 — — EP disclosed
US-4310612-A NUCLEOPHILIC DISPLACEMENT EASTMAN KODAK COMPANY (US) 1982-01-12 — — US disclosed
US-4197080-A Radiation-cleavable nondiffusible compounds and photographic elements and processes employing them EASTMAN KODAK COMPANY (US) 1980-04-08 — — US disclosed
US-4165987-A Photographic products and processes employing novel nondiffusible pyridylazopyrazole or pyrimidylazopyrazole dye-releasing compounds EASTMAN KODAK COMPANY (US) 1979-08-28 — — US disclosed
US-4165987-A Photographic products and processes employing novel nondiffusible pyridylazopyrazole or pyrimidylazopyrazole dye-releasing compounds EASTMAN KODAK COMPANY (US) 1979-08-28 — — US disclosed
US-4165987-A Photographic products and processes employing novel nondiffusible pyridylazopyrazole or pyrimidylazopyrazole dye-releasing compounds EASTMAN KODAK COMPANY (US) 1979-08-28 — — US disclosed
US-4148641-A DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1979-04-10 — — US disclosed
US-4148641-A DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1979-04-10 — — US disclosed
US-4148641-A DIFFUSION TRANSFER EASTMAN KODAK COMPANY (US) 1979-04-10 — — US disclosed
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