Bromide

Bromide

SCHEMBL10885367

[Br-].c1ccc(C[S+](Cc2ccccc2)Cc2ccccc2)cc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.47
TSHR P16473 4/20 0.43
ALDH1A1 P00352 3/20 0.43
IDO1 P14902 3/20 0.43
LOXL2 Q9Y4K0 2/20 0.43
TP53 P04637 1/20 0.43
TRPA1 O75762 1/20 0.43
MAOB P27338 1/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
ALOX12 P18054 1/20 0.41
CASP1 P29466 1/20 0.41
HSD17B10 Q99714 1/20 0.41
TDP1 Q9NUW8 2/20 0.39
CYP2A6 P11509 1/20 0.39
HTR2A P28223 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
TAAR1 Q96RJ0 1/20 0.39
THRB P10828 1/20 0.38
EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL247179 0.97 CALM1 (0.50) CALM1TSHRALDH1A1IDO1LOXL2
Iodide SCHEMBL10884305 0.94 CALM1 (0.47) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL9498864 0.88 CALM1 (0.43) CALM1TSHRALDH1A1IDO1LOXL2
Bromide SCHEMBL29399740 0.84 TP53 (0.48) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL9456777 0.84 CALM1 (0.39) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL396269 0.80 TP53 (0.50) CALM1TSHRALDH1A1IDO1LOXL2
SCHEMBL8973723 0.80 TP53 (0.50) CALM1TSHRALDH1A1IDO1LOXL2
Sulfuric Acid SCHEMBL9457320 0.80 CA2 (0.41) CALM1TSHRIDO1HSD17B10CES2
SCHEMBL8587004 0.79 TSHR (0.48) CALM1TSHRALDH1A1IDO1LOXL2
Hydrochloric Acid SCHEMBL967040 0.78 TP53 (0.48) CALM1TSHRALDH1A1IDO1LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4478751-A Complex salts having high electric conductivity BAYER AKTIENGESELLSCHAFT (DE) 1984-10-23 US claimed
EP-0073379-B1 COMPLEX SALTS WITH INCREASED ELECTRICAL CONDUCTIVITY BAYER AG (DE) 1986-08-13 EP disclosed
US-4478751-A Complex salts having high electric conductivity BAYER AKTIENGESELLSCHAFT (DE) 1984-10-23 US disclosed
EP-0073379-A1 Complex salts with increased electrical conductivity BAYER AG (DE) 1983-03-09 EP disclosed