⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL351498 | 0.85 | TSHR (0.31) | — | |
| SCHEMBL8063039 | 0.83 | SMN1; SMN2 (0.43) | — | |
| SCHEMBL11056937 | 0.75 | HPGD (0.39) | — | |
| SCHEMBL10882956 | 0.73 | THRB (0.39) | — | |
| SCHEMBL30596831 | 0.73 | TYMS (0.42) | — | |
| SCHEMBL331642 | 0.73 | TYMS (0.42) | — | |
| SCHEMBL2868698 | 0.73 | THRB (0.46) | — | |
| SCHEMBL10794143 | 0.72 | THRA (0.32) | — | |
| SCHEMBL11106263 | 0.72 | ALDH1A1 (0.40) | — | |
| SCHEMBL28283315 | 0.72 | PSMB5 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095932-B1 | THE USE OF A PARTICULATE POLYMER AS A CARRIER FOR BIOLOGICAL SUBSTANCES AND THE LIKE AND SUCH SUBSTANCES SUPPORTED ON THE CARRIER | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1986-08-06 | — | — | EP | claimed |
| EP-0095932-B1 | THE USE OF A PARTICULATE POLYMER AS A CARRIER FOR BIOLOGICAL SUBSTANCES AND THE LIKE AND SUCH SUBSTANCES SUPPORTED ON THE CARRIER | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1986-08-06 | — | — | EP | disclosed |
| EP-0095932-A1 | The use of a particulate polymer as a carrier for biological substances and the like and such substances supported on the carrier | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1983-12-07 | — | — | EP | disclosed |