SCHEMBL2868698

SCHEMBL2868698

C=CC(=O)OC(Oc1ccccc1)C(C)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
GAA P10253 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2C9 P11712 1/20 0.38
PKM P14618 1/20 0.38
CYP2C19 P33261 1/20 0.38
KMT2A Q03164 3/20 0.38
MEN1 O00255 2/20 0.38
MAPT P10636 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
HCAR2 Q8TDS4 1/20 0.36
LMNA P02545 2/20 0.36
ALDH1A1 P00352 1/20 0.36
TP53 P04637 1/20 0.36
HPGD P15428 1/20 0.36
KDM4E B2RXH2 2/20 0.36
HTT P42858 1/20 0.36
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22578982 0.89 RXRA (0.47) THRBGAACYP1A2CYP2C9PKM
SCHEMBL4953833 0.89 PTGS1 (0.46) THRBKMT2AMEN1LMNAALDH1A1
SCHEMBL28525484 0.88 THRB (0.46) THRBMTNR1AMTNR1BGAACYP1A2
SCHEMBL11354877 0.85 LMNA (0.43) THRBKMT2AMEN1LMNAALDH1A1
SCHEMBL34034 0.82 THRB (0.46) THRBMTNR1AMTNR1BGAACYP1A2
Water SCHEMBL28126876 0.81 THRB (0.45) THRBMTNR1AMTNR1BGAACYP1A2
SCHEMBL11056937 0.81 HPGD (0.39) THRBCYP1A2KMT2AMEN1ALDH1A1
SCHEMBL11106263 0.80 ALDH1A1 (0.40) GAAPKMKMT2AMEN1MAPT
SCHEMBL11681892 0.80 PPARG (0.38) THRBLMNAALDH1A1HPGDKDM4E
SCHEMBL21383345 0.80 THRB (0.46) THRBPSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2101745-A1 DELIVERY OF DRUGS LANDEC CORPORATION (US) 2009-09-23 EP claimed
WO-2008070118-A9 DRUG DELIVERY LANDEC CORP (US) 2008-09-18 WO claimed
WO-2008070118-A1 DRUG DELIVERY LANDEC CORPORATION (US) 2008-06-12 WO claimed
US-4614761-A Process for producing curable resin SHOWA HIGHPOLYMER CO., LTD. (JP) 1986-09-30 US claimed
CN-113544120-A Novel compound, composition containing same, and cured product 株式会社ADEKA 2021-10-22 CN disclosed
US-8372492-B2 crosslinked copolymer of butyl acrylate and phenoxyethyl acrylate; prevent liquid crystal display unevenness in a peripheral portion of a display screen; durability, nonsettling, no defects NITTO DENKO CORPORATION (JP) 2013-02-12 US disclosed
CN-1703475-B Flexible emissive coatings for elastomer substrates LORD CORP 2011-01-12 CN disclosed
US-7798625-B2 Active ray curable ink-jet ink set, image forming method and ink-jet recording apparatus KONICA MINOLTA MEDICAL & GRAPHIC, INC. (JP) 2010-09-21 US disclosed
US-20100149076-A1 COMPOSITION FOR PREPARING PHOSPHOR LAYER, PLASMA DISPLAY PANEL AND METHOD OF MANUFACTURING THE PLASMA DISPLAY PANEL SAMSUNG SDI CO., LTD. (KR) 2010-06-17 US disclosed
US-20100148659-A1 PLASMA DISPLAY PANEL AND METHOD OF MANUFACTURING THE SAME SAMSUNG SDI CO., LTD. (KR) 2010-06-17 US disclosed
EP-2065348-B1 Paste composition for plasma display device and associated methods SAMSUNG SDI CO LTD (KR) 2010-06-16 EP disclosed
EP-2101745-A1 DELIVERY OF DRUGS LANDEC CORPORATION (US) 2009-09-23 EP disclosed
EP-0168126-A1 Process for producing a curable resin SHOWA HIGHPOLYMER CO., LTD. (JP) 1986-01-15 EP disclosed
US-4552604-A EPOXY RESINS, PHOTOPOLYMERIZATION, LAMINATION CIBA GEIGY CORPORATION (US) 1985-11-12 US disclosed
US-4424100-A MONOUNSATURATED AND POLYUNSATURATED COMPOUNDS MOBIL OIL CORPORATION (US) 1984-01-03 US disclosed
EP-0082603-A2 Radiation curable epoxy/acrylate-hydroxyl coating compositions MOBIL OIL CORPORATION (US) 1983-06-29 EP disclosed
US-4254012-A Reinforced composites containing cyanato resins CIBA-GEIGY CORPORATION (US) 1981-03-03 US disclosed
EP-0018776-A2 Radiation curable coating compositions, process for preparing such compositions and substrates coated therewith MOBIL OIL CORPORATION (US) 1980-11-12 EP disclosed
US-4125503-A Ultraviolet curing emulsion systems MOBIL OIL CORPORATION (US) 1978-11-14 US disclosed
US-4072592-A ADDUCT OF ACRYLIC ACID AND EPOXY RESIN MOBIL OIL CORPORATION (US) 1978-02-07 US disclosed