Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPN | P05981 | 1/20 | 0.66 |
| ▸ | MAPT | P10636 | 1/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.66 |
| ▸ | VCAM1 | P19320 | 13/20 | 0.51 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.48 |
| ▸ | GLRB | P48167 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8703731 | 0.85 | HPN (0.66) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL11742580 | 0.85 | HPN (0.66) | HPNMAPTALOX15SIRT5VCAM1 | |
| Probucol SCHEMBL4150 | 0.80 | HPN (1.00) | HPNMAPTALOX15SIRT5VCAM1 | |
| Probucol SCHEMBL5143451 | 0.80 | HPN (1.00) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9328009 | 0.80 | HPN (0.58) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL9506457 | 0.78 | HPN (0.79) | HPNMAPTALOX15SIRT5VCAM1 | |
| Probucol SCHEMBL4620631 | 0.78 | ALOX15 (0.95) | HPNMAPTALOX15SIRT5VCAM1 | |
| Probucol SCHEMBL8344652 | 0.78 | ALOX15 (0.95) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL11734771 | 0.77 | HPN (0.54) | HPNMAPTALOX15SIRT5VCAM1 | |
| SCHEMBL4985953 | 0.77 | HPN (0.84) | HPNMAPTALOX15SIRT5VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0116517-B1 | ESTER OR ANHYDRIDE OF SUBSTITUTED 4-(HYDROXYPHENYL-THIO)-SUCCINIC ACID | CIBA-GEIGY AG (CH) | 1986-06-18 | — | — | EP | claimed |
| EP-0116517-B1 | ESTER OR ANHYDRIDE OF SUBSTITUTED 4-(HYDROXYPHENYL-THIO)-SUCCINIC ACID | CIBA-GEIGY AG (CH) | 1986-06-18 | — | — | EP | disclosed |
| EP-0116517-A1 | Ester or anhydride of substituted 4-(hydroxyphenyl-thio)-succinic acid | CIBA-GEIGY AG (CH) | 1984-08-22 | — | — | EP | disclosed |