Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.58 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | KIF11 | P52732 | 5/20 | 0.53 |
| ▸ | AGXT | P21549 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.51 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.51 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263793 | 1.00 | MEN1 (0.58) | MEN1KMT2ADRD2DRD3ALDH1A1 | |
| Hydrochloric Acid SCHEMBL10646814 | 0.98 | MEN1 (0.56) | MEN1KMT2ADRD2DRD3ALDH1A1 | |
| SCHEMBL1599836 | 0.98 | MEN1 (0.60) | MEN1KMT2ADRD2DRD3ALDH1A1 | |
| SCHEMBL29774627 | 0.98 | MEN1 (0.60) | MEN1KMT2ADRD2DRD3ALDH1A1 | |
| SCHEMBL17144785 | 0.94 | MEN1 (0.60) | MEN1KMT2ADRD2DRD3ALDH1A1 | |
| SCHEMBL29914690 | 0.94 | MEN1 (0.60) | MEN1KMT2ADRD2DRD3ALDH1A1 | |
| SCHEMBL9723025 | 0.89 | DRD2 (0.68) | MEN1KMT2ADRD2DRD3ALDH1A1 | |
| SCHEMBL22685038 | 0.84 | ALDH1A1 (0.59) | MEN1KMT2AALDH1A1GAAKDM4E | |
| SCHEMBL6348865 | 0.82 | CHRNB2 (0.60) | DRD2DRD3ALDH1A1HTTMAPT | |
| Phenol SCHEMBL28279448 | 0.81 | ALDH1A1 (0.53) | MEN1KMT2AALDH1A1GAAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082599-B1 | M-HYDROXYPHENYL SUBSTITUTED COMPOUNDS | JOHN WYETH & BROTHER LIMITED (GB) | 1986-01-15 | — | — | EP | disclosed |
| US-4463177-A | Process for making m-hydroxyphenyl substituted compounds | JOHN WYETH & BROTHER LIMITED (GB) | 1984-07-31 | — | — | US | disclosed |
| EP-0082599-A1 | m-Hydroxyphenyl substituted compounds | JOHN WYETH & BROTHER LIMITED (GB) | 1983-06-29 | — | — | EP | disclosed |