SCHEMBL69177

SCHEMBL69177

COC(=O)c1ncccc1-c1cccnc1C(=O)OC

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 4/20 0.64
ALOX15 P16050 2/20 0.47
MAP2K1 Q02750 1/20 0.47
HTT P42858 1/20 0.47
ALDH1A1 P00352 4/20 0.47
NPSR1 Q6W5P4 2/20 0.46
KDM4E B2RXH2 6/20 0.46
TDP1 Q9NUW8 1/20 0.46
STAT3 P40763 1/20 0.46
HIF1A Q16665 1/20 0.46
BRD4 O60885 1/20 0.44
HPGD P15428 1/20 0.43
TDP2 O95551 1/20 0.43
TSHR P16473 2/20 0.42
MAPT P10636 2/20 0.42
CYP3A4 P08684 1/20 0.42
BLM P54132 1/20 0.42
AGER Q15109 1/20 0.42
PARP1 P09874 1/20 0.42
PKM P14618 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7812554 0.93 L3MBTL1 (0.57) L3MBTL1ALOX15MAP2K1HTTALDH1A1
SCHEMBL25307003 0.88 L3MBTL1 (0.53) L3MBTL1ALDH1A1KDM4EHPGDPKM
SCHEMBL22290177 0.88 L3MBTL1 (0.53) L3MBTL1ALOX15MAP2K1HTTALDH1A1
SCHEMBL698991 0.88 L3MBTL1 (0.55) L3MBTL1HTTALDH1A1KDM4ETDP1
SCHEMBL30775035 0.85 L3MBTL1 (0.53) L3MBTL1ALOX15MAP2K1HTTALDH1A1
SCHEMBL28865711 0.84 L3MBTL1 (0.51) L3MBTL1ALOX15MAP2K1HTTALDH1A1
SCHEMBL30499558 0.84 SLC6A4 (0.59) L3MBTL1ALDH1A1KDM4E
SCHEMBL22290184 0.84 SLC6A4 (0.59) L3MBTL1ALDH1A1KDM4E
SCHEMBL9301522 0.84 SLC6A3 (0.57) L3MBTL1ALOX15MAP2K1HTTMAPT
SCHEMBL13734214 0.84 L3MBTL1 (0.51) L3MBTL1ALOX15MAP2K1HTTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2479203-A1 AROMATIC POLYESTER Muroran Institute of Technology (JP) 2012-07-25 EP disclosed
US-20120172570-A1 AROMATIC POLYESTER NITTA CORPORATION 2012-07-05 US disclosed
US-8129493-B2 Aromatic polyester MURORAN INSTITUTE OF TECHNOLOGY (JP) 2012-03-06 US disclosed
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME MURORAN INSTITUTE OF TECHNOLOGY (JP) 2011-09-15 US disclosed
US-20110092662-A1 AROMATIC POLYESTER NITTA CORPORATION (JP) 2011-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110224343-A1 MODIFIER FOR AROMATIC POLYESTER AND AROMATIC POLYESTER RESIN COMPOSITION COMPRISING THE SAME F12, PHAX, WDR82 L3MBTL1 4274/4885ALOX15 1966/4885MAP2K1 2957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.