Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LAP3 | P28838 | 2/20 | 0.31 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.31 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.30 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.30 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.30 |
| ▸ | PGK1 | P00558 | 1/20 | 0.30 |
| ▸ | PGK2 | P07205 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433467 | 0.75 | SMPD1 (0.43) | SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL5848596 | 0.74 | MEN1 (0.41) | CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL2710380 | 0.72 | HMGCR (0.38) | CYP2D6CYP2C19SMPD1LPAR3LPAR1 | |
| SCHEMBL1923665 | 0.71 | SMPD1 (0.46) | SMPD1LPAR3LPAR1LPAR2 | |
| Phosphoric Acid SCHEMBL11537484 | 0.70 | LPAR3 (0.35) | SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL15338706 | 0.70 | LMNA (0.36) | SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL31116893 | 0.70 | SMPD1 (0.40) | SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL2473447 | 0.69 | ALDH1A1 (0.39) | SMPD1LPAR3LPAR1LPAR2 | |
| SCHEMBL4486615 | 0.69 | — | — | |
| SCHEMBL15966669 | 0.68 | FDPS (0.44) | SMPD1LPAR3LPAR1LPAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4591583-A | TREATING VIRAL INFECTIONS | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1986-05-27 | — | — | US | disclosed |
| US-4386081-A | VIRICIDE | ASTRA LAKEMEDEL AKTIEBOLAG (SE) | 1983-05-31 | — | — | US | disclosed |
| EP-0003007-B1 | ALIPHATIC DERIVATIVES OF PHOSPHONOFORMIC ACID, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR COMBATING VIRUS INFECTIONS | Astra Läkemedel Aktiebolag (SE) | 1982-04-07 | — | — | EP | disclosed |
| EP-0003007-A2 | Aliphatic derivatives of phosphonoformic acid, pharmaceutical compositions and methods for combating virus infections | Astra Läkemedel Aktiebolag (SE) | 1979-07-11 | — | — | EP | disclosed |