Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 10/20 | 0.31 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433467 | 0.77 | SMPD1 (0.43) | LPAR3LPAR2LPAR1SMPD1FDPS | |
| SCHEMBL15338706 | 0.71 | LMNA (0.36) | LPAR3LPAR2LPAR1SMPD1FDPS | |
| SCHEMBL10889136 | 0.70 | CYP1A2 (0.32) | LPAR3LPAR2LPAR1SMPD1 | |
| SCHEMBL26044020 | 0.69 | — | — | |
| SCHEMBL1923665 | 0.68 | SMPD1 (0.46) | LPAR3LPAR2LPAR1SMPD1FDPS | |
| SCHEMBL19126524 | 0.68 | TRPM8 (0.34) | — | |
| SCHEMBL16592090 | 0.68 | TP53 (0.31) | — | |
| SCHEMBL18822070 | 0.68 | SMPD1 (0.37) | LPAR3LPAR2LPAR1SMPD1 | |
| Phosphoric Acid SCHEMBL27351310 | 0.68 | LMNA (0.47) | LPAR3LPAR1FDPSGGPS1LMNA | |
| Phosphoric Acid SCHEMBL28535853 | 0.67 | FDPS (0.46) | LPAR3LPAR1SMPD1FDPSLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4137065-A | HERBICIDE, INSECTICIDE, NEMATOCIDE, MITICIDE | SUMITOMO CHEMICAL COMPANY, LTD. (JP) | 1979-01-30 | — | — | US | disclosed |