Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497297 | 0.82 | KMT2A (0.44) | KMT2AALDH1A1TSHRADRB2ADRB1 | |
| SCHEMBL6952030 | 0.79 | ALDH1A1 (0.59) | KMT2AALDH1A1TSHRADRB2ADRB1 | |
| SCHEMBL8549771 | 0.79 | ALDH1A1 (0.59) | KMT2AALDH1A1TSHRADRB2ADRB1 | |
| SCHEMBL8673620 | 0.76 | TSHR (0.53) | KMT2AALDH1A1TSHRCYP1A2SMN1; SMN2 | |
| SCHEMBL13168067 | 0.76 | ALDH1A1 (0.47) | KMT2AALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL10688255 | 0.75 | KMT2A (0.38) | KMT2AALDH1A1TSHRMEN1RECQL | |
| SCHEMBL129333 | 0.74 | TSHR (0.55) | KMT2AALDH1A1TSHRCYP1A2SMN1; SMN2 | |
| SCHEMBL13647304 | 0.74 | KMT2A (0.46) | KMT2AALDH1A1TSHRCYP1A2CYP2D6 | |
| SCHEMBL23817190 | 0.73 | KMT2A (0.44) | KMT2AALDH1A1TSHRADRB2ADRB1 | |
| SCHEMBL22474313 | 0.73 | KMT2A (0.44) | KMT2AALDH1A1TSHRADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4619985-A | Process for the production of deactivated suspensions of finely-divided polyisocyanates in relatively high molecular weight compounds, deactivated suspensions and use thereof for the production of polyurethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1986-10-28 | — | — | US | disclosed |
| US-4595445-A | Adhesive is thermosetting reactive polyisocyanate-polyamine activated by heat or polar solvents | BAYER AKTIENGESELLSCHAFT (DE) | 1986-06-17 | — | — | US | disclosed |
| US-4546165-A | Process for the production of stabilized polyisocyanates of retarded reactivity and their use in the production of polyurethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-08 | — | — | US | disclosed |