Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22474252 | 0.84 | SLC6A4 (0.46) | KMT2ACYP1A2CYP2D6SMN1; SMN2PKM | |
| SCHEMBL7325641 | 0.84 | KMT2A (0.46) | KMT2ACYP1A2CYP2D6SMN1; SMN2PKM | |
| SCHEMBL7325650 | 0.84 | KMT2A (0.46) | KMT2ACYP1A2CYP2D6SMN1; SMN2PKM | |
| SCHEMBL7325646 | 0.84 | KMT2A (0.46) | KMT2ACYP1A2CYP2D6SMN1; SMN2PKM | |
| SCHEMBL13168067 | 0.83 | ALDH1A1 (0.47) | KMT2ACYP1A2CYP2D6SMN1; SMN2PKM | |
| SCHEMBL19275401 | 0.82 | CA12 (0.50) | KMT2ACYP1A2CYP2D6SMN1; SMN2PKM | |
| SCHEMBL13168062 | 0.81 | APAF1 (0.42) | KMT2ACYP1A2CYP2D6SMN1; SMN2PKM | |
| SCHEMBL23817190 | 0.80 | KMT2A (0.44) | KMT2ACYP1A2CYP2D6SMN1; SMN2PKM | |
| SCHEMBL8549771 | 0.80 | ALDH1A1 (0.59) | KMT2ALMNAALDH1A1TSHRADRB2 | |
| SCHEMBL4352840 | 0.79 | LMNA (0.52) | KMT2ACYP1A2CYP2D6SMN1; SMN2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3255991-B1 | PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2020-09-30 | — | — | EP | disclosed |