Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 2/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.60 |
| ▸ | ADRB3 | P13945 | 4/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11448213 | 0.82 | MAPT (0.93) | MAPTHTTSMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL10889271 | 0.81 | MAPT (0.77) | MAPTHTTSMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL1116411 | 0.76 | MAPK1 (0.61) | MAPTHTTSMN1; SMN2MAPK1ALOX15 | |
| SCHEMBL6818065 | 0.75 | ADRB1 (1.00) | ADRB1ADRB3ADRB2CYP1A2ALOX15 | |
| SCHEMBL12648565 | 0.75 | ADRB1 (1.00) | ADRB1ADRB3ADRB2CYP1A2ALOX15 | |
| SCHEMBL17086818 | 0.75 | ADRB1 (1.00) | ADRB1ADRB3ADRB2CYP1A2ALOX15 | |
| Hydrochloric Acid SCHEMBL2342247 | 0.74 | ADRB1 (0.97) | ADRB1ADRB3ADRB2CYP1A2ALOX15 | |
| Hydrochloric Acid SCHEMBL2342254 | 0.74 | ADRB1 (0.97) | ADRB1ADRB3ADRB2CYP1A2ALOX15 | |
| SCHEMBL13736891 | 0.74 | MAPT (0.68) | MAPTHTTSMN1; SMN2ADRB1ADRB3 | |
| SCHEMBL7801099 | 0.74 | MAPK1 (0.58) | MAPTHTTSMN1; SMN2MAPK1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6890955-B2 | Aryloxypropanolamine derivatives, method of preparation and applications thereof | VIRBAC SA (FR) | 2005-05-10 | — | — | US | disclosed |
| US-20030158259-A1 | Aryloxypropanolamine derivatives, method of preparation and applications thereof | VIRBAC SA | 2003-08-21 | — | — | US | disclosed |
| US-20020019440-A1 | Aryloxypropanolamine derivatives, method of preparation and applications thereof | VIRBAC SA | 2002-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020019440-A1 | Aryloxypropanolamine derivatives, method of preparation and applications thereof | FABP4, CCNO, PAOX | MAPT 4771/4885HTT 2184/4885SMN1; SMN2 4000/4885 |
| US-20030158259-A1 | Aryloxypropanolamine derivatives, method of preparation and applications thereof | PAOX, ACOX3, FABP4 | MAPT 4830/4885HTT 2390/4885SMN1; SMN2 4009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.