Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11238954 | 0.84 | MAPT (0.47) | MAPTSMN1; SMN2LMNA | |
| SCHEMBL11237823 | 0.84 | MAPT (0.42) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL11235230 | 0.83 | MAPT (0.46) | MAPTSMN1; SMN2LMNA | |
| Hydrochloric Acid SCHEMBL11236940 | 0.83 | MAPT (0.41) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL11234636 | 0.83 | HTT (0.41) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL11230529 | 0.82 | MAPT (0.50) | MAPTSMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL11230236 | 0.80 | ALDH1A1 (0.50) | MAPTSMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL10889271 | 0.79 | MAPT (0.77) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11246095 | 0.79 | RAB9A (0.46) | MAPTNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL11246086 | 0.79 | MAPT (0.63) | MAPTMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4356322-A | ADRENERGIC STIMULANTS; CARDIOTONIC AGENTS | VEB ARZNEIMITTELWERK DRESDEN (DD) | 1982-10-26 | — | — | US | claimed |