Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | IARS1 | P41252 | 1/20 | 0.38 |
| ▸ | DAPK1 | P53355 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.38 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10889183 | 0.72 | ADORA2A (0.39) | RAB9AKMT2APDE4APDE4BPDE4C | |
| SCHEMBL10896726 | 0.67 | ADCY5 (0.40) | ADORA2A | |
| SCHEMBL10902555 | 0.67 | ADCY5 (0.40) | ADORA2A | |
| SCHEMBL14028468 | 0.67 | ADORA2A (0.59) | RAB9AKMT2ADAPK1ADORA2ATMIGD3 | |
| SCHEMBL2979897 | 0.66 | ADORA2A (0.68) | KMT2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL10773324 | 0.65 | CTRB1 (0.54) | ATMMAPT | |
| SCHEMBL10773321 | 0.65 | CTRB1 (0.54) | ATMMAPT | |
| SCHEMBL9554893 | 0.65 | ATM (0.53) | ATMTDP1MAPT | |
| SCHEMBL29451987 | 0.65 | CTRB1 (0.54) | ATMMAPT | |
| SCHEMBL10645951 | 0.65 | OPRD1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077460-B1 | PURINE COMPOUNDS ENDOWED WITH IMMUNOMODULATING ACTIVITY | CO PHARMA CORPORATION S.r.l. (IT) | 1986-10-15 | — | — | EP | disclosed |
| US-4567182-A | PURINE DERIVATIVES | CO PHARMA CORPORATION S.R.L. (IT) | 1986-01-28 | — | — | US | disclosed |