Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7501359 | 0.89 | ALDH1A1 (0.52) | ALDH1A1MAPTLMNASMN1; SMN2EPHX1 | |
| SCHEMBL10789373 | 0.89 | TDP1 (0.58) | ALDH1A1MAPTLMNASMN1; SMN2EPHX1 | |
| SCHEMBL9431268 | 0.84 | BRD4 (0.64) | LMNASMN1; SMN2BRD4 | |
| SCHEMBL5657703 | 0.83 | ALDH1A1 (0.66) | ALDH1A1MAPTLMNAEPHX1TDP1 | |
| SCHEMBL7789182 | 0.80 | LMNA (0.50) | LMNASMN1; SMN2 | |
| SCHEMBL13741593 | 0.79 | DRD2 (0.51) | ALDH1A1MAPTLMNASMN1; SMN2TDP1 | |
| SCHEMBL19672050 | 0.78 | SMN1; SMN2 (0.43) | ALDH1A1MAPTLMNASMN1; SMN2HSD17B1 | |
| SCHEMBL24535027 | 0.78 | LMNA (0.48) | ALDH1A1LMNASMN1; SMN2CYP1A2CYP2C19 | |
| SCHEMBL9182141 | 0.77 | EPHX1 (0.74) | ALDH1A1MAPTLMNASMN1; SMN2EPHX1 | |
| SCHEMBL7501346 | 0.77 | KDM4E (0.44) | ALDH1A1SMN1; SMN2EPHX1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600797-A | NITRATING AN AMINOBENZENE WHICH HAS A PROTECTEDD AMINO GROUP | BAYER AKTIENGESELLSCHAFT (DE) | 1986-07-15 | — | — | US | disclosed |