Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884703 | 0.72 | ALDH1A1 (0.41) | TSHRALDH1A1HTT | |
| SCHEMBL10884534 | 0.71 | TSHR (0.44) | TSHRMAPTMEN1KMT2ACYP1A2 | |
| SCHEMBL19927729 | 0.71 | NFKB1 (0.35) | TSHRSMN1; SMN2POLBHPGD | |
| SCHEMBL19968798 | 0.71 | NFKB1 (0.35) | TSHRSMN1; SMN2POLBHPGD | |
| SCHEMBL18179524 | 0.68 | SMN1; SMN2 (0.35) | TSHRMAPTMEN1KMT2AALDH1A1 | |
| SCHEMBL4815395 | 0.62 | NR1D1 (0.48) | TSHRMAPTPKMMEN1KMT2A | |
| SCHEMBL14193309 | 0.62 | NR1D1 (0.48) | TSHRMAPTPKMMEN1KMT2A | |
| SCHEMBL4135351 | 0.62 | MAPT (0.62) | TSHRMAPTPKMSIGMAR1MEN1 | |
| SCHEMBL4129635 | 0.62 | MAPT (0.62) | TSHRMAPTPKMSIGMAR1MEN1 | |
| SCHEMBL22640217 | 0.62 | TSHR (0.55) | TSHRMAPTPKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0097124-B1 | PROCESS FOR THE PHOTOPOLYMERISATION OF UNSATURATED COMPOUNDS | CIBA-GEIGY AG (CH) | 1986-10-15 | — | — | EP | disclosed |
| US-4498964-A | PHOTOINITIATORS FOR HIGH-SPEED CURING OF PRINTING INKS, PAINTS, PHOTORESISTS AND FILMS | CIBA-GEIGY CORPORATION (US) | 1985-02-12 | — | — | US | disclosed |