Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | SLC27A1 | Q6PCB7 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893914 | 0.84 | ABL1 (0.44) | TSHRNPC1RAB9ASLC27A1LMNA | |
| Hydrochloric Acid SCHEMBL10889776 | 0.82 | ABL1 (0.43) | TSHRNPC1RAB9ASLC27A1LMNA | |
| SCHEMBL10891333 | 0.78 | TSHR (0.38) | TSHRNPC1RAB9ALMNAMAPT | |
| SCHEMBL10888736 | 0.78 | PDK1 (0.33) | NPC1RAB9ASLC27A1LMNATP53 | |
| SCHEMBL6999293 | 0.74 | TSHR (0.61) | TSHRNPC1RAB9ALMNAMAPT | |
| SCHEMBL10890832 | 0.73 | NPC1 (0.37) | TSHRNPC1RAB9ASLC27A1LMNA | |
| Hydrochloric Acid SCHEMBL10891755 | 0.72 | NPC1 (0.36) | TSHRNPC1RAB9ASLC27A1LMNA | |
| SCHEMBL11054645 | 0.69 | MEN1 (0.61) | NPC1RAB9AMAPTTP53ALDH1A1 | |
| SCHEMBL10893459 | 0.68 | APOBEC3A (0.49) | TSHRNPC1RAB9ALMNAMAPT | |
| SCHEMBL11057384 | 0.68 | GAA (0.50) | MAPTALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4600722-A | 3-amino-1-(4,5,6,7-tetrahydro-benzothiazolyl)-2-pyrazolines and a process for the treatment of inflammatory or allergic processes in humans | A. NATTERMANN & CIE GMBH (DE) | 1986-07-15 | — | — | US | disclosed |