Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ACP1 | P24666 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890496 | 0.84 | MAPT (0.40) | MAPTKDM4EACP1LMNACSNK1D | |
| SCHEMBL10895474 | 0.77 | MAPT (0.46) | MAPTKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL9304708 | 0.76 | ALDH1A1 (0.38) | MAPTACP1LMNAALDH1A1MEN1 | |
| SCHEMBL11323730 | 0.74 | LMNA (0.40) | MAPTKDM4ELMNAMEN1KMT2A | |
| SCHEMBL21983967 | 0.73 | POLB (0.47) | MAPTKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10893468 | 0.73 | RAB9A (0.59) | MAPTLMNACSNK1DALDH1A1MEN1 | |
| SCHEMBL11119676 | 0.71 | HTT (0.50) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL10889118 | 0.70 | NPBWR1 (0.51) | KDM4EALDH1A1 | |
| SCHEMBL14508173 | 0.70 | ELANE (0.40) | MAPTKDM4ELMNAALDH1A1MEN1 | |
| SCHEMBL9304726 | 0.68 | CTSA (0.38) | MAPTLMNAALDH1A1TP53CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4612049-A | BENZOTHI ZOLYL THIO-, BENZIMIDAZOLYLTHIO- OR BENZOXAZOLYLTHIO-SUBSTITUTED CARBOXY ACID | CIBA-GEIGY CORPORATION (US) | 1986-09-16 | — | — | US | disclosed |