Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890654 | 0.81 | ESR1 (0.46) | ESR1ESR2ALDH1A1CYP3A4TSHR | |
| SCHEMBL10889760 | 0.73 | MEN1 (0.43) | ALDH1A1POLBMAPTCYP3A4CYP2C19 | |
| SCHEMBL10356346 | 0.73 | ESR1 (0.39) | ESR1ESR2ALDH1A1CYP3A4TYR | |
| SCHEMBL10356748 | 0.73 | ESR1 (0.36) | ESR1ESR2ARTYRHSP90AB1 | |
| SCHEMBL10356402 | 0.71 | KIF11 (0.42) | ESR1ESR2CYP3A4AR | |
| SCHEMBL10356413 | 0.71 | ESR1 (0.42) | ESR1ESR2POLBMAPTAR | |
| SCHEMBL10356747 | 0.71 | ESR1 (0.39) | ESR1ESR2MAPTCYP3A4TSHR | |
| SCHEMBL10356407 | 0.71 | TTR (0.43) | ALDH1A1MAPTCYP3A4TSHRTP53 | |
| SCHEMBL8912157 | 0.69 | ALDH1A1 (0.50) | ESR1ALDH1A1POLBMAPTTSHR | |
| SCHEMBL10356362 | 0.69 | MAPT (0.43) | ALDH1A1POLBMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0112587-B1 | DERIVATIVES OF 4-(1-(PHENYL)-1-(HYDROXY)-PROP-1-YL)-RESORCINE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-09-19 | — | — | EP | claimed |
| EP-0112587-A2 | Derivatives of 4-(1-(phenyl)-1-(hydroxy)-prop-1-yl)-resorcine, process for their preparation and medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-07-04 | — | — | EP | claimed |
| EP-0112587-B1 | DERIVATIVES OF 4-(1-(PHENYL)-1-(HYDROXY)-PROP-1-YL)-RESORCINE, PROCESS FOR THEIR PREPARATION AND MEDICINES CONTAINING THESE COMPOUNDS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1990-09-19 | — | — | EP | disclosed |
| US-4510338-A | TREATMENT OF ACUTE ETHANOLIC INTOXICATION/- | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1985-04-09 | — | — | US | disclosed |
| EP-0112587-A2 | Derivatives of 4-(1-(phenyl)-1-(hydroxy)-prop-1-yl)-resorcine, process for their preparation and medicines containing these compounds | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1984-07-04 | — | — | EP | disclosed |