Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10892240 | 0.90 | TYR (0.39) | ALOX15TP53CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL10888796 | 0.85 | TYR (0.40) | ALOX15TP53CYP2C9TYRALOX5 | |
| SCHEMBL10891739 | 0.78 | CYP2C9 (0.54) | ALOX15TP53CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL10890691 | 0.75 | TYR (0.42) | ALOX15TP53CYP2C9CYP2C19TYR | |
| SCHEMBL10893342 | 0.75 | TYR (0.42) | ALOX15TP53CYP2C9TYRALOX5 | |
| SCHEMBL10894988 | 0.74 | ALOX5 (0.43) | ALOX15TP53CYP2C9TYRALOX5 | |
| SCHEMBL10892097 | 0.74 | TYR (0.41) | ALOX15TP53CYP2C9TYRALOX5 | |
| SCHEMBL10752094 | 0.73 | ALOX15 (0.64) | ALOX15TP53CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL30640814 | 0.72 | HTT (0.47) | ALOX15TP53CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL10892121 | 0.72 | TYR (0.39) | ALOX15TP53CYP2C9TYRALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584146-A | Tetrakis(2,6-di-t-butyl-4-substituted phenyl)4,4'-bisphenyl diphosphites | THE B. F. GOODRICH COMPANY (US) | 1986-04-22 | — | — | US | disclosed |