SCHEMBL10891739

SCHEMBL10891739

CCCC(c1c(C)cc(O)cc1C(C)(C)C)c1c(C)cc(O)cc1C(C)(C)C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 6/20 0.54
ALOX15 P16050 6/20 0.54
CYP2C19 P33261 5/20 0.54
TP53 P04637 2/20 0.54
CYP2D6 P10635 2/20 0.54
ALDH1A1 P00352 4/20 0.35
TYR P14679 2/20 0.35
HSD17B10 Q99714 2/20 0.35
NR1I2 O75469 1/20 0.35
LMNA P02545 1/20 0.35
MIF P14174 1/20 0.35
HTT P42858 1/20 0.35
NFE2L2 Q16236 1/20 0.35
CYP1A2 P05177 3/20 0.34
SMN1; SMN2 Q16637 4/20 0.33
CA2 P00918 2/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ATP2A2 P16615 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10001301 0.86 ALOX15 (0.74) CYP2C9ALOX15CYP2C19TP53CYP2D6
SCHEMBL3892652 0.81 CYP2C9 (0.36) CYP2C9ALOX15CYP2C19TP53CYP2D6
SCHEMBL2903683 0.79 ALOX15 (0.36) CYP2C9ALOX15CYP2C19TP53CYP2D6
SCHEMBL10890992 0.78 ALOX15 (0.42) CYP2C9ALOX15CYP2C19TP53CYP2D6
SCHEMBL10938482 0.77 ALOX15 (0.41) CYP2C9ALOX15CYP2C19TP53CYP2D6
SCHEMBL8922674 0.76 CYP2C9 (0.57) CYP2C9ALOX15CYP2C19TP53CYP2D6
SCHEMBL29363860 0.73 CYP2C9 (0.50) CYP2C9ALOX15CYP2C19TP53CYP2D6
SCHEMBL808447 0.73 CYP2C9 (0.50) CYP2C9ALOX15CYP2C19TP53CYP2D6
SCHEMBL5710060 0.72 PTGS2 (0.46) CYP3A4
SCHEMBL31544922 0.70 TP53 (0.41) CYP2C9ALOX15CYP2C19TP53CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0069195-A2 Stabilized ethylene/chlorotrifluoroethylene copolymer composition Ausimont, U.S.A., Inc. (US) 1983-01-12 EP claimed
WO-2023112417-A1 METHOD FOR PRODUCING POLY(PHENYLENE ETHER) 太陽ホールディングス株式会社 2023-06-22 WO disclosed
US-4584146-A Tetrakis(2,6-di-t-butyl-4-substituted phenyl)4,4'-bisphenyl diphosphites THE B. F. GOODRICH COMPANY (US) 1986-04-22 US disclosed
US-4413077-A Oligomeric aromatic polyphosphites BORG-WARNER CHEMICALS, INC. (US) 1983-11-01 US disclosed