Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 3/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10890992 | 0.90 | ALOX15 (0.42) | TYRALOX5PTGS2CYP3A4CYP2C9 | |
| SCHEMBL10888796 | 0.86 | TYR (0.40) | TYRALOX5PTGS2CYP3A4CYP2C9 | |
| SCHEMBL10890691 | 0.76 | TYR (0.42) | TYRALOX5PTGS2CYP3A4CYP2C9 | |
| SCHEMBL10893342 | 0.76 | TYR (0.42) | TYRALOX5PTGS2CYP3A4CYP2C9 | |
| SCHEMBL10894988 | 0.75 | ALOX5 (0.43) | TYRALOX5PTGS2CYP3A4CYP2C9 | |
| SCHEMBL10892097 | 0.75 | TYR (0.41) | TYRALOX5PTGS2CYP3A4CYP2C9 | |
| SCHEMBL225100 | 0.74 | PTGS2 (0.48) | TYRALOX5PTGS2CYP3A4TSHR | |
| SCHEMBL30640814 | 0.73 | HTT (0.47) | TYRPTGS2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10892121 | 0.73 | TYR (0.39) | TYRALOX5PTGS2CYP3A4CYP2C9 | |
| SCHEMBL10891309 | 0.73 | TYR (0.39) | TYRALOX5PTGS2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584146-A | Tetrakis(2,6-di-t-butyl-4-substituted phenyl)4,4'-bisphenyl diphosphites | THE B. F. GOODRICH COMPANY (US) | 1986-04-22 | — | — | US | disclosed |