Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.59 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | HTR2A | P28223 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29531112 | 0.96 | CNR1 (0.59) | CNR1MCHR1CHRM1HTR2AKCNH2 | |
| SCHEMBL30673014 | 0.83 | CNR1 (0.50) | CNR1MCHR1CHRM1HTR2AKCNH2 | |
| SCHEMBL14175271 | 0.82 | MAPT (0.55) | ALDH1A1ACHEKDM4EMEN1POLB | |
| SCHEMBL23671492 | 0.82 | SIGMAR1 (0.56) | SIGMAR1ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL4804050 | 0.82 | ALDH1A1 (0.50) | MCHR1SIGMAR1ALDH1A1ACHEMEN1 | |
| SCHEMBL30673001 | 0.82 | CNR1 (0.52) | CNR1MCHR1KCNH2SIGMAR1ALDH1A1 | |
| SCHEMBL8673780 | 0.81 | POLB (0.59) | SIGMAR1ALDH1A1ACHEMEN1POLB | |
| SCHEMBL12440015 | 0.81 | MCHR1 (0.69) | CNR1MCHR1CHRM1HTR2AKCNH2 | |
| SCHEMBL2259794 | 0.80 | ALDH1A1 (0.47) | CNR1MCHR1SIGMAR1ALDH1A1GAA | |
| SCHEMBL13102339 | 0.80 | MAPT (0.57) | ALDH1A1ACHEKDM4EMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4596891-A | PHENYL-N,N'-DIETHYLETHYLENE DIAMINES | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1986-06-24 | — | — | US | disclosed |
| US-4286983-A | INCLUDING COMPOUNDS OF THE N-PHENYL-N',N'-DIETHYL ALKYLENEDIAMINE TYPE | DUPHAR INTERNATIONAL RESEARCH B.V. (NL) | 1981-09-01 | — | — | US | disclosed |