Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | ESRRG | P62508 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2259794 | 0.98 | ALDH1A1 (0.47) | ALDH1A1ESRRGLTA4HPTGS1PTGS2 | |
| Hydrochloric Acid SCHEMBL4809872 | 0.96 | ALDH1A1 (0.46) | ALDH1A1ESRRGLTA4HPTGS1PTGS2 | |
| SCHEMBL18570582 | 0.91 | APP (0.43) | ESRRGLTA4HPTGS1PTGS2ADRA2A | |
| SCHEMBL3988708 | 0.88 | BACE1 (0.50) | ALDH1A1LTA4HPTGS1PTGS2SIGMAR1 | |
| Hydrochloric Acid SCHEMBL4808510 | 0.86 | BACE1 (0.49) | ALDH1A1ESRRGLTA4HPTGS1PTGS2 | |
| SCHEMBL31606858 | 0.84 | LMNA (0.54) | ALDH1A1ADRA2CGAAKDM1ASIGMAR1 | |
| SCHEMBL23963161 | 0.83 | CHRM1 (0.49) | ESRRGL3MBTL1SIGMAR1MCHR1HRH3 | |
| SCHEMBL3222264 | 0.83 | CD274 (0.55) | ALDH1A1GAAL3MBTL1KDM1AAPAF1 | |
| SCHEMBL10891769 | 0.82 | CNR1 (0.59) | ALDH1A1GAASIGMAR1MCHR1HRH3 | |
| SCHEMBL23671492 | 0.82 | SIGMAR1 (0.56) | ALDH1A1ESRRGLTA4HPTGS2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338536-B2 | N-alkylamino secondary para-phenylenediamine, composition for dyeing keratin fibers comprising such a para-phenylenediamine, processes using this composition and uses thereof | L'OREAL S. A. (FR) | 2008-03-04 | — | — | US | claimed |
| US-20060026772-A1 | N-alkylamino secondary para-phenylenediamine, composition for dyeing keratin fibers comprising such a para-phenylenediamine, processes using this composition and uses thereof | L'OREAL | 2006-02-09 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060026772-A1 | N-alkylamino secondary para-phenylenediamine, composition for dyeing keratin fibers comprising such a para-phenylenediamine, processes using this composition and uses thereof | KRT18, CDC73, PRKDC | ALDH1A1 1045/4885ESRRG 4115/4885LTA4H 4151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.