Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | CASP6 | P55212 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ELAVL1 | Q15717 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10892420 | 0.79 | CYP2C9 (0.47) | RAPGEF4GAAALDH1A1POLBRECQL | |
| SCHEMBL10891189 | 0.77 | GAA (0.52) | GAAALDH1A1POLBRECQLKMT2A | |
| SCHEMBL10892269 | 0.72 | SMN1; SMN2 (0.48) | RAPGEF4GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL343355 | 0.72 | RAPGEF4 (0.65) | RAPGEF4GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL10635283 | 0.72 | RAPGEF4 (0.44) | RAPGEF4GAAMAPTL3MBTL1KDM4E | |
| SCHEMBL5856927 | 0.72 | HDAC4 (0.47) | GAAALDH1A1TDP1KMT2AHTR6 | |
| SCHEMBL14574205 | 0.70 | LMNA (0.50) | ALDH1A1POLBTDP1KMT2AHSD17B10 | |
| SCHEMBL10894138 | 0.69 | SMN1; SMN2 (0.46) | GAAL3MBTL1KDM4EALDH1A1TDP1 | |
| SCHEMBL12004944 | 0.69 | TAAR1 (0.37) | GAAMAPTHTR6 | |
| Hydrochloric Acid SCHEMBL10889858 | 0.69 | SMN1; SMN2 (0.45) | GAAMAPTL3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588810-A | Basic triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | disclosed |
| EP-0148390-A2 | Basic triphendioxazine dyes, their manufacture and their use | BAYER AG (DE) | 1985-07-17 | — | — | EP | disclosed |