Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | TYR | P14679 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.37 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9721890 | 0.78 | CA2 (0.48) | ALOX15ALDH1A1CYP2C9TYRNR1I2 | |
| SCHEMBL2327164 | 0.76 | ALOX15 (0.46) | ALOX15ALDH1A1CYP2C9TYRNR1I2 | |
| SCHEMBL9244951 | 0.73 | ALDH1A1 (0.46) | ALOX15ALDH1A1CYP2C9TYRNR1I2 | |
| SCHEMBL11449784 | 0.73 | GABRA1 (0.42) | ALOX15ALDH1A1CYP2C9TYRNR1I2 | |
| SCHEMBL5377400 | 0.72 | ALDH1A1 (0.57) | ALOX15ALDH1A1CYP2C9TYRNR1I2 | |
| Propofol SCHEMBL11596465 | 0.70 | CA2 (0.61) | ALOX15ALDH1A1CYP2C9TYRNR1I2 | |
| SCHEMBL18176646 | 0.69 | ALDH1A1 (0.54) | ALOX15ALDH1A1CYP2C9TYRNR1I2 | |
| SCHEMBL15894570 | 0.69 | CA2 (0.48) | ALOX15ALDH1A1CYP2C9TYRNR1I2 | |
| SCHEMBL24344601 | 0.68 | CYP1A2 (0.38) | CYP1A2GABRA1GABRB2CYP2D6 | |
| SCHEMBL3132119 | 0.68 | HPN (0.50) | ALOX15ALDH1A1CYP2C9TYRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584146-A | Tetrakis(2,6-di-t-butyl-4-substituted phenyl)4,4'-bisphenyl diphosphites | THE B. F. GOODRICH COMPANY (US) | 1986-04-22 | — | — | US | disclosed |