Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10895262 | 0.93 | L3MBTL3 (0.50) | SIGMAR1ALDH1A1MAPK1GFERL3MBTL3 | |
| SCHEMBL10893396 | 0.91 | L3MBTL3 (0.46) | SIGMAR1ALDH1A1MAPK1GFERL3MBTL3 | |
| SCHEMBL10893133 | 0.88 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1MAPK1GFERKMT2A | |
| SCHEMBL10894769 | 0.84 | SIGMAR1 (0.51) | SIGMAR1ALDH1A1MAPK1GFERKMT2A | |
| SCHEMBL10894158 | 0.84 | GAA (0.50) | ALDH1A1KMT2AL3MBTL3CYP2C19 | |
| Hydrochloric Acid SCHEMBL10894674 | 0.82 | GAA (0.49) | ALDH1A1KMT2AL3MBTL3CYP2C19 | |
| SCHEMBL10893391 | 0.81 | GAA (0.36) | ALDH1A1MAPK1SLC22A2SLC22A1LMNA | |
| SCHEMBL10889640 | 0.81 | CA12 (0.39) | ALDH1A1GFERKMT2ALMNA | |
| SCHEMBL10894580 | 0.80 | CHEK1 (0.45) | SIGMAR1ALDH1A1MAPK1KMT2ASLC22A2 | |
| SCHEMBL10894194 | 0.80 | SERPINE1 (0.36) | ALDH1A1MAPK1GFERKMT2ASLC22A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588810-A | Basic triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | disclosed |