Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.44 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.43 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893133 | 0.85 | SIGMAR1 (0.48) | SIGMAR1ALDH1A1MAPK1GFERKMT2A | |
| SCHEMBL10891838 | 0.84 | SIGMAR1 (0.47) | SIGMAR1ALDH1A1MAPK1GFERKMT2A | |
| SCHEMBL11434946 | 0.81 | KMT2A (0.57) | SIGMAR1ALDH1A1MAPK1GFERKMT2A | |
| SCHEMBL10894896 | 0.80 | GAA (0.56) | ALDH1A1KMT2AL3MBTL3TSHRCYP2C19 | |
| SCHEMBL1674212 | 0.79 | SIGMAR1 (0.74) | SIGMAR1ALDH1A1MAPK1GFERKMT2A | |
| SCHEMBL17774565 | 0.78 | RECQL (0.54) | ALDH1A1MAPK1KMT2ALMNATSHR | |
| SCHEMBL16364931 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TSHRCYP2C19 | |
| SCHEMBL2848726 | 0.77 | SIGMAR1 (0.58) | SIGMAR1ALDH1A1MAPK1GFERKMT2A | |
| SCHEMBL10895262 | 0.77 | L3MBTL3 (0.50) | SIGMAR1ALDH1A1MAPK1GFERL3MBTL3 | |
| SCHEMBL10893396 | 0.76 | L3MBTL3 (0.46) | SIGMAR1ALDH1A1MAPK1GFERL3MBTL3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588810-A | Basic triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | disclosed |