Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MELK | Q14680 | 2/20 | 0.36 |
| ▸ | METAP2 | P50579 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10891838 | 0.81 | SIGMAR1 (0.47) | LMNAALDH1A1SLC22A2SLC22A1TSHR | |
| SCHEMBL10895262 | 0.79 | L3MBTL3 (0.50) | GAAMETAP2ALDH1A1MAPK1 | |
| SCHEMBL10893396 | 0.78 | L3MBTL3 (0.46) | MELKMETAP2ALDH1A1MAPK1 | |
| SCHEMBL10894194 | 0.76 | SERPINE1 (0.36) | GAAMAPTLMNAALDH1A1L3MBTL1 | |
| SCHEMBL10889054 | 0.72 | METAP2 (0.45) | GAAMAPTMELKMETAP2LMNA | |
| SCHEMBL9750234 | 0.72 | L3MBTL1 (0.39) | GAAMAPTCA12CA2CA9 | |
| SCHEMBL10894580 | 0.71 | CHEK1 (0.45) | MAPTMETAP2CA2CA9LMNA | |
| SCHEMBL10894158 | 0.70 | GAA (0.50) | GAASMN1; SMN2CA12CA2CA9 | |
| SCHEMBL9083398 | 0.70 | RAPGEF4 (0.59) | GAAMAPTLMNAALDH1A1L3MBTL1 | |
| SCHEMBL10893133 | 0.69 | SIGMAR1 (0.48) | LMNAALDH1A1SLC22A2SLC22A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4588810-A | Basic triphendioxazine dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1986-05-13 | — | — | US | disclosed |