Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.34 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.34 |
| ▸ | NSD2 | O96028 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10813403 | 0.83 | TOP2B (0.45) | POLBPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL7771196 | 0.71 | MAOA (0.40) | POLBPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL7122665 | 0.65 | MEN1 (0.54) | POLBPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL728510 | 0.64 | MEN1 (0.60) | POLBPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL187595 | 0.62 | MAPT (0.74) | POLBKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL31171427 | 0.62 | MAPT (0.74) | POLBKMT2AMEN1ALDH1A1L3MBTL1 | |
| SCHEMBL7129845 | 0.62 | L3MBTL1 (0.53) | POLBPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL11046426 | 0.61 | MAOA (0.51) | POLBKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL10891910 | 0.60 | KMT2A (0.48) | POLBPKMKMT2AMEN1ALDH1A1 | |
| SCHEMBL13370299 | 0.60 | MEN1 (0.54) | POLBPKMKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0122417-A3 | POLYMERIC(((OXAZOLIDINYL)ALKYL)AMINO)ANTHRAQUINONES | AMERICAN CYANAMID COMPANY (US) | 1986-01-08 | — | — | EP | disclosed |
| EP-0122417-A2 | Polymeric(((oxazolidinyl)alkyl)amino)anthraquinones | AMERICAN CYANAMID COMPANY (US) | 1984-10-24 | — | — | EP | disclosed |