Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.47 |
| ▸ | TYR | P14679 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.40 |
| ▸ | BID | P55957 | 3/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.40 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.40 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.40 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9744224 | 0.95 | PTGS2 (0.51) | ALOX5PTGS2TYRMEN1TP53 | |
| SCHEMBL10933792 | 0.87 | TYR (0.46) | ALOX5PTGS2TYRMEN1TP53 | |
| SCHEMBL20102183 | 0.85 | DHFR (0.43) | ALOX5PTGS2CYP3A4HTTELANE | |
| SCHEMBL10894467 | 0.85 | ALOX5 (0.46) | ALOX5PTGS2TYRMEN1TP53 | |
| SCHEMBL10894181 | 0.85 | ALOX5 (0.46) | ALOX5PTGS2TYRMEN1TP53 | |
| SCHEMBL9745295 | 0.85 | ALOX5 (0.46) | ALOX5PTGS2TYRMEN1TP53 | |
| SCHEMBL10407157 | 0.84 | PTGS2 (0.51) | ALOX5PTGS2TYRMEN1TP53 | |
| SCHEMBL2678101 | 0.83 | GABRA1 (0.48) | CYP3A4MAPTALOX15HTT | |
| SCHEMBL1022144 | 0.82 | PTGS2 (0.58) | ALOX5PTGS2TYRMEN1TP53 | |
| SCHEMBL1023098 | 0.82 | PTGS2 (0.50) | ALOX5PTGS2TYRMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4626259-A | ADDITIVE OF ORGANIC NITRATE IGNITION ACCELERATOR AND 4,4'-THIOBISPHENOLS; REDUCED COKING OF INJECTOR NOZZLES | ETHYL CORPORATION (US) | 1986-12-02 | — | — | US | claimed |
| US-4626259-A | ADDITIVE OF ORGANIC NITRATE IGNITION ACCELERATOR AND 4,4'-THIOBISPHENOLS; REDUCED COKING OF INJECTOR NOZZLES | ETHYL CORPORATION (US) | 1986-12-02 | — | — | US | disclosed |