Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | G6PD | P11413 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8779422 | 0.83 | ALDH1A1 (0.68) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL10566898 | 0.81 | RAB9A (0.56) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL13411701 | 0.78 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL11540934 | 0.77 | SMN1; SMN2 (0.66) | ALDH1A1SMN1; SMN2RAB9ANPC1ALOX15 | |
| SCHEMBL11723544 | 0.77 | RAB9A (0.57) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL11625570 | 0.75 | TP53 (0.61) | RAB9ANPC1TP53LMNAMAPT | |
| SCHEMBL9720512 | 0.75 | RAB9A (0.67) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL10889232 | 0.73 | MAPT (0.63) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL10800511 | 0.73 | RAB9A (0.57) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB | |
| SCHEMBL15503847 | 0.72 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2RAB9ANPC1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4599424-A | PRE-AND POSTEMERGENCE | RHONE-POULENC, INC. (US) | 1986-07-08 | — | — | US | disclosed |
| US-4175081-A | PLANT GROWTH REGULATORS, HERBICIDES | MOBIL OIL CORPORATION (US) | 1979-11-20 | — | — | US | disclosed |