Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.64 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10800511 | 0.91 | RAB9A (0.57) | RAB9AMAPTNPC1SMN1; SMN2HTT | |
| SCHEMBL11540934 | 0.88 | SMN1; SMN2 (0.66) | RAB9AMAPTNPC1SMN1; SMN2HTT | |
| SCHEMBL8779347 | 0.84 | RAB9A (0.63) | RAB9AMAPTNPC1SMN1; SMN2HTT | |
| SCHEMBL11625570 | 0.82 | TP53 (0.61) | RAB9AMAPTNPC1LMNATP53 | |
| SCHEMBL8356401 | 0.81 | SMN1; SMN2 (0.61) | RAB9AMAPTNPC1SMN1; SMN2HTT | |
| SCHEMBL10889232 | 0.79 | MAPT (0.63) | RAB9AMAPTNPC1SMN1; SMN2HTT | |
| SCHEMBL10566898 | 0.79 | RAB9A (0.56) | RAB9AMAPTNPC1SMN1; SMN2HTT | |
| SCHEMBL11717238 | 0.79 | RAB9A (0.55) | RAB9AMAPTNPC1SMN1; SMN2HTT | |
| SCHEMBL13411701 | 0.76 | ALDH1A1 (0.49) | RAB9ANPC1SMN1; SMN2HTTMEN1 | |
| SCHEMBL10892136 | 0.75 | ALDH1A1 (0.64) | RAB9AMAPTNPC1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5087284-A | 5-substituted thiadiazole ureas and their use as herbicides | RHONE-POULENC, INC. (US) | 1992-02-11 | — | — | US | disclosed |
| US-4599424-A | PRE-AND POSTEMERGENCE | RHONE-POULENC, INC. (US) | 1986-07-08 | — | — | US | disclosed |
| US-4175081-A | PLANT GROWTH REGULATORS, HERBICIDES | MOBIL OIL CORPORATION (US) | 1979-11-20 | — | — | US | disclosed |