SCHEMBL10892159

SCHEMBL10892159

COc1ccc(-c2ccoc2C(=O)O)cc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.49
PPARG P37231 1/20 0.49
KDM4E B2RXH2 1/20 0.47
NPC1 O15118 1/20 0.47
POLB P06746 1/20 0.47
HMGB1 P09429 1/20 0.47
MAPT P10636 1/20 0.47
RAB9A P51151 1/20 0.47
SLC22A12 Q96S37 1/20 0.46
EGFR P00533 1/20 0.45
KDR P35968 1/20 0.45
GAA P10253 2/20 0.43
TUBB4A P04350 1/20 0.42
TUBB P07437 1/20 0.42
TUBA3C P0DPH7 1/20 0.42
TUBA1B P68363 1/20 0.42
TUBA4A P68366 1/20 0.42
TUBB4B P68371 1/20 0.42
TUBB3 Q13509 1/20 0.42
TUBB2A Q13885 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31325726 0.84 SLC22A12 (0.42) KDM4ENPC1POLBMAPTRAB9A
SCHEMBL10873515 0.74 ERN1 (0.58) KDM4ENPC1MAPTTUBB4ATUBB
SCHEMBL3983853 0.73 HSD17B10 (0.47) PTPN1POLBMAPTRAB9A
SCHEMBL5153364 0.72 CHRNA4 (0.49) KDM4EPOLBMAPTRAB9A
SCHEMBL31325662 0.72 HSD17B10 (0.40) KDM4EPOLBMAPTSLC22A12GAA
SCHEMBL31325669 0.72 ALDH1A1 (0.45) KDM4ENPC1MAPTRAB9AGAA
SCHEMBL14081310 0.72 TUBB4A (0.51) POLBMAPTEGFRKDRGAA
SCHEMBL2318665 0.72 SMN1; SMN2 (0.42) KDM4ENPC1POLBMAPTRAB9A
SCHEMBL3979501 0.71 HPGDS (0.47)
SCHEMBL2323369 0.70 KMO (0.46) NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4602095-A 3-hydroxy-4-alkyloxyphenyl heterocyclic aromatic carboxylates GENERAL FOODS CORPORATION (US) 1986-07-22 US disclosed