Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10893157 | 1.00 | KEAP1 (0.32) | KEAP1NFE2L2HCAR2MAPTPKM | |
| SCHEMBL11018842 | 0.85 | TBXA2R (0.35) | ALDH1A1 | |
| SCHEMBL10891016 | 0.80 | HCAR2 (0.34) | KEAP1NFE2L2HCAR2MAPTALDH1A1 | |
| SCHEMBL10790152 | 0.80 | HCAR2 (0.34) | KEAP1NFE2L2HCAR2MAPTALDH1A1 | |
| SCHEMBL8835495 | 0.76 | PGR (0.34) | KEAP1NFE2L2HCAR2MAPTALDH1A1 | |
| SCHEMBL16289019 | 0.76 | HCAR2 (0.41) | KEAP1NFE2L2HCAR2MAPTALDH1A1 | |
| SCHEMBL11623426 | 0.72 | PTGER2 (0.47) | ALDH1A1 | |
| SCHEMBL16287745 | 0.71 | HCAR2 (0.40) | KEAP1NFE2L2HCAR2MAPTALDH1A1 | |
| SCHEMBL29626505 | 0.71 | HCAR2 (0.57) | KEAP1NFE2L2HCAR2MAPTALDH1A1 | |
| SCHEMBL5023381 | 0.69 | HCAR2 (0.50) | KEAP1NFE2L2HCAR2MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4622339-A | ANTICOAGULANTS, ANTIISCHEMIC, ANTIATHEROSCLEROTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1986-11-11 | — | — | US | disclosed |