Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.32 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL854814 | 0.93 | TSHR (0.48) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL1189490 | 0.86 | ADRB2 (0.38) | TSHRCYP3A4SMN1; SMN2ALDH1A1ADRB2 | |
| SCHEMBL837875 | 0.86 | ADRB2 (0.38) | TSHRCYP3A4SMN1; SMN2ALDH1A1ADRB2 | |
| SCHEMBL10356609 | 0.83 | TSHR (0.43) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL7109570 | 0.80 | TSHR (0.44) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL7109465 | 0.80 | TSHR (0.44) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL6292792 | 0.79 | CA1 (0.33) | TSHRMEN1THRBHTTKMT2A | |
| SCHEMBL8607727 | 0.79 | TSHR (0.48) | TSHRCYP3A4MEN1THRBHTT | |
| SCHEMBL93421 | 0.78 | ADRB2 (0.43) | TSHRCYP3A4THRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL14201357 | 0.77 | TSHR (0.41) | TSHRCYP3A4MEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4613451-A | SELF-CURING COATING | PPG INDUSTRIES, INC. (US) | 1986-09-23 | — | — | US | disclosed |
| US-4501872-A | FILMS; COATINGS; SELF-CURING AT LOW TEMPERATURES | PPG INDUSTRIES, INC. (US) | 1985-02-26 | — | — | US | disclosed |
| US-4467081-A | Gelable, silicate rich resins from hydrophobic polyols and volatile and/or incompatible organosilicates | PPG INDUSTRIES, INC. (US) | 1984-08-21 | — | — | US | disclosed |
| US-4446292-A | Moisture curable compositions containing reaction products of hydrophobic polyols and monomer organosilicon-containing substances | PPG INDUSTRIES, INC. (US) | 1984-05-01 | — | — | US | disclosed |